10.18453/rosdok_id00002352
Do, Huy Hoang
Huy Hoang
Do
http://d-nb.info/gnd/114505692X
Synthesis of functionalized heterocycles via palladium catalyzed cross-coupling reactions
Universität Rostock
2017
540 Chemistry & allied sciences
2017
en
http://purl.uni-rostock.de/rosdok/id00002352
urn:nbn:de:gbv:28-diss2018-0179-5
This present thesis is dedicated to the design and the synthesis of novel biologically active and fluorescent heterocycles from common starting materials. Based on Palldium(0) catalyzed reactions, a series of new ethynylated naphthalenes, ethynylated naphthaleneindoles, benzo[b]carbazolediones, benzofuroindoles and furodiindoles were synthesized with high yield. Synthesized compounds show interesting fluorescence properties with high quantum yields (19-78%). The benzocarbazolediones can be used as selective inhibitors against nucleotide pyrophosphatase.