Malik,  Imran

Synthesis of Substituted Dibenzothiophenes, Pyrazines, Quinoxalines, Flavones, Pyrimidines and Furans by Regioselective Palladium (0)-Catalyzed Cross-Coupling Reactions

Rostock : Universität , 2010

https://doi.org/10.18453/rosdok_id00000807

http://purl.uni-rostock.de/rosdok/id00000807

Abstract:

The palladium(0)-catalyzed Heck reactions of brominated benzothiophene provided functionalized dibenzothiophenes by 6π-electro cyclization reactions. Heck reactions of dichloropyrazine and quinoxaline provided dialkenyl-, 2-alkenyl-3-alkyl and dialkylpyrazines and quinoxalines. Suzuki-Miyaura reactions of the bis(triflate) of 7,8- dihyroxyflavone with arylboronic acids afforded aryl-substituted flavones with excellent site-selectivity. Sonogashira reactions of tetrachloropyrimidine and tetrabromofuran provided di-, tri-, tetra-alkynylated and mixed Sonogashira-Suzuki products with excellent fluorescence properties.

Dissertation Open Access