zum Inhalt

 

El-Kased,  Reham Farag

Novel Mass Spectrometry-based Epitope Mapping Procedures of Autoantigens

Rostock : Universität , 2010

https://doi.org/10.18453/rosdok_id00000828

http://purl.uni-rostock.de/rosdok/id00000828

Abstract:

Preventive medicine for patients is to be realized from monitoring and management of early stage disease rather than from late stage treatment. Among the strategies of preventive medicine is the detection of prognostic and diagnostic protein signatures, in particular epitopes against which autoantibodies in blood plasma are directed during the progression of the disease. Recognizing such diseasespecific antibodies in patient screenings requires knowledge of the respective epitopes. In this work, novel mass spectrometry-based methodologies for epitope mapping of autoantigens are described.

Dissertation Open Access


Einrichtung :
Universitätsmedizin
Gutachter :
Glocker,  Michael O.  (Prof. Dr.)
Shmitt,  Michael  (Prof. Dr. med.)
Tholey,  Andreas  (Prof. Dr.)
Jahr der Abgabe:
2010
Jahr der Verteidigung:
2011
Sprache(n) :
Englisch
Schlagworte:
epitope mapping, mass spectrometry, autoantigen, autoantibod
DDC Klassifikation :
610 Medizin, Gesundheit
URN :
urn:nbn:de:gbv:28-diss2011-0054-1
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00000828
erstellt am:
2012-03-13
zuletzt geändert am:
2018-06-30
Volltext