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Morgan,  Peter James

Characterisation of calcium signalling and functional development in an immortalised human neural progenitor cell line

Rostock : Universität , 2011

https://doi.org/10.18453/rosdok_id00001088

http://purl.uni-rostock.de/rosdok/id00001088

Abstract:

The development of an immortalised hNPC line, ReNcell VM, was investigated in standard cell cultures and after transplantation on to hippocampal organotypical brain slice cultures. Whole cell patch clamp recordings and Calcium imaging were used to characterise the functional development during proliferation and differentiation. The findings of this study provide insights into the functional properties of hNPCs, and identify a new method by which their development might be controlled in culture.

Dissertation Open Access


Einrichtung :
Mathematisch-Naturwissenschaftliche Fakultät
Gutachter :
Weiss,  Dieter  (Prof. Dr.)
Rolfs,  Arndt  (Prof. Dr.)
Jahr der Abgabe:
2012
Jahr der Verteidigung:
2012
Sprache(n) :
Englisch
Schlagworte:
patch-clamp, imaging, veratridine
DDC Klassifikation :
570 Biowissenschaften, Biologie
URN :
urn:nbn:de:gbv:28-diss2013-0001-6
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00001088
erstellt am:
2013-01-08
zuletzt geändert am:
2018-06-30
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