Sprache(n) : |
|
übersetzter Titel
:
|
Effect of 17β-estradiol and genistein on cultured vascular smooth muscle and endothelial cells and characterization of tissue responses to 17β-estradiol and genistein-eluting stents in porcine cultured blood vessels |
|
übersetzte Zusammenfassung
:
|
The percutaneous coronary intervention with implantation of a stent is the preferred method for the treatment of cardiovascular diseases. The aim is the further development of drug-eluting stents that significantly reduce the rate of restenosis. In this work 17β-estradiol and genistein were examined for the effect on vascular cells and cultured blood vessels. At the cellular and tissue level 17β-estradiol provides no cardio protective properties. The local release of genistein can improve the vascular healing response. It represents an option in the development of new drug-eluting stents. |
|
Schlagworte: |
Atherosklerose, Restenose, Late Stent Thrombose, atherosclerosis, restenosis |
|
DDC Klassifikation : |
610 Medizin, Gesundheit |
580 Pflanzen (Botanik) |
|