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Jegannathan,  Jaya Shanmuga Prakash

Improved synthesis of 2,3-diacetamidouronates which are present in bacterial envelope

Rostock : Universität , 2014

https://doi.org/10.18453/rosdok_id00001253

http://purl.uni-rostock.de/rosdok/id00001253

Abstract:

Diacetamidodideoxyuronic acids are components of lipopolysaccarides present in bacterial cell wall. There are very few publications reporting the preparation of this class of sugars. Hence, we present the synthesis of gluco-, galacto- and manno- configured sugars of 2,3-diacetamido-2,3-dideoxy-D-uronates. These monosaccharaides can be employed as glycosyl donors and acceptors in glycosylation reactions to produce larger glycosylates which can serve as components of antibiotics. Currently, the target molecules were synthesized in high yields with good reproducibility and scalability.

Dissertation Open Access


Einrichtung :
Mathematisch-Naturwissenschaftliche Fakultät
Gutachter :
Vogel,  Christian  (Prof. Dr.)
Opatz,  Till  (Prof. Dr.)
Jahr der Abgabe:
2013
Jahr der Verteidigung:
2013
Sprache(n) :
Englisch
Schlagworte:
carbohydrate chemistry, total synthesis, bio-organic chemistry
DDC Klassifikation :
540 Chemie
URN :
urn:nbn:de:gbv:28-diss2014-0005-4
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00001253
erstellt am:
2014-01-10
zuletzt geändert am:
2018-06-30
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