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Abbasi,  Muhammad Shakeel Ahmed

Annulation reactions of heterocyclic chlorovinyl-aldehydes  : synthesis of functionalized 6H-benzo[c]chromen-6-ones (biaryl lactones), 6H-benzo[c]chromenes and heteroannulated pyridines

Rostock : Universität , 2015

https://doi.org/10.18453/rosdok_id00001536

http://purl.uni-rostock.de/rosdok/id00001536

Abstract:

A simple and convenient domino cycloaromatization approach towards the synthesis of novel benzo[c]chromen-6-ones and benzo[c]chromenes by treatment of heterocyclic chlorovinyl-aldehydes with active methylene compounds has been developed. In another strategy novel biaryl lactones were prepared by Sonogashira cross-coupling and base catalyzed reactions of 4-chloro-2-oxo-2H-chromene-3-carbaldehyde with terminal alkynes and 1, 3-dicarbonyl compounds.Finally some heterocyclic chlorovinyl-aldehydes were treated with electron rich heterocyclic amines to afford novel heteroannulated pyridines.

Dissertation Open Access


Einrichtung :
Mathematisch-Naturwissenschaftliche Fakultät
Gutachter :
Langer,  Peter  (Prof. Dr.)
Schmidt,  Bernd  (Prof. Dr.)
Jahr der Abgabe:
2014
Jahr der Verteidigung:
2015
Sprache(n) :
Englisch
Schlagworte:
Heterocycles, Palladium, Domino cyclization reactions
DDC Klassifikation :
540 Chemie
URN :
urn:nbn:de:gbv:28-diss2015-0086-0
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00001536
erstellt am:
2015-06-01
zuletzt geändert am:
2018-06-30
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