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Al-Abo,  Aws Mardan Hamdy

Synthesis of functionalized isatins, benzoxazoles, isoflavones, coumarins, by site-selective Suzuki-Miyaura cross-coupling reactions

Rostock : Universität , 2015

https://doi.org/10.18453/rosdok_id00001647

http://purl.uni-rostock.de/rosdok/id00001647

Abstract:

This thesis includes regioselective palladium catalyzed Suzuki-Miyaura cross coupling reactions of isatins benzoxazols isoflavones and coumarins. These classes of compounds are of pharmacological relevance. Suzuki-Miyaura cross-coupling reactions of dichloro methylindolinen dione afforded arylated isatins. The reactions proceeded with very good site selectivity. The Suzuki-Miyaura reaction of dichlorobenzoxazol, of the bis(triflate) of dihydroxyisoflavone, and of the bis(triflate) of methyl dihydroxycoumarin, with different boronic acids, gave the corresponding site-selective mono-arylated, homo bis-arylated and mixed bis-arylated derivaties, most of them with very good site-selectivity.

Dissertation Open Access


Einrichtung :
Mathematisch-Naturwissenschaftliche Fakultät
Gutachter :
Kaufmann,  Dieter E.  (Prof. Dr)
Langer,  Peter  (Prof. Dr)
Jahr der Abgabe:
2015
Jahr der Verteidigung:
2015
Sprache(n) :
Englisch
Schlagworte:
palladium, flavones, hetrocyclic
DDC Klassifikation :
540 Chemie
URN :
urn:nbn:de:gbv:28-diss2015-0197-1
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00001647
erstellt am:
2015-12-08
zuletzt geändert am:
2018-06-30
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