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Skorska,  Anna

Identification and characterization of CD4+AT2R+ T cell subpopulation in humans and rats

Rostock : Universität , 2016

https://doi.org/10.18453/rosdok_id00001764

http://purl.uni-rostock.de/rosdok/id00001764

Abstract:

The study contributes to the understanding of CD4+AT2R+ cell function after myocardial infarction (MI). This potential novel T cell subset, which expresses FoxP3 and various cytokines improves cardiac function and reduces infarct size. Results indicate that the CD4+AT2R+ T cells might be included in therapeutic approaches for the treatment of cardiac diseases, due to its upregulation in the infarcted state. The application of this T cell subset may improve the healing process of compromised heart tissue and contribute to a better quality of life in affected patients.

Dissertation Open Access


Einrichtung :
Universitätsmedizin
Gutachter :
Steinhoff,  Gustav  (Prof. Dr. med.)
Vollmar,  Brigitte  (Prof. Dr. med.)
Volk,  Hans-Dieter  (Prof. Dr. med.)
Jahr der Abgabe:
2015
Jahr der Verteidigung:
2016
Sprache(n) :
Englisch
übersetzter Titel :
Identifizierung und Charakterisierung der CD4+AT2R+ T Zell Subpopulation bei Mensch und Ratte
Schlagworte:
angiotensin II type 2 receptor, renin angiotensin system, myocardial infarction, CD4+ T lymphocytes
DDC Klassifikation :
610 Medizin, Gesundheit
URN :
urn:nbn:de:gbv:28-diss2016-0077-5
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00001764
erstellt am:
2016-07-05
zuletzt geändert am:
2018-06-30
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