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Mörke,  Caroline

Caveolae-mediated phagocytosis of biomaterial surface structures by human osteoblasts

Rostock : Universität , 2016

https://doi.org/10.18453/rosdok_id00001785

http://purl.uni-rostock.de/rosdok/id00001785

Abstract:

Cells are sensitive to their underlying topography, which evoke large ranges of cell responses. The work describes an attempted caveolae-mediated phagocytosis of the surface-fixed micro-pillars by human MG-63 osteoblastic cells. This attempt to phagocytize the elevations of the Ti surface results in higher energy requirements for the cells and finally to impaired osteoblast function. Similar cell responses were observed for the osteoblasts treated with micro-particles as phagocytosis trigger and osteoblasts growing on stochastic rough Ti surfaces, commercially used as implant surfaces.

Dissertation Open Access


Einrichtung :
Universitätsmedizin
Gutachter :
Nebe,  Barbara  (Prof. Dr.)
Kuznetsov,  Sergei A.  (PD Dr.)
de Boer,  Jan  (Prof. Dr.)
Jahr der Abgabe:
2016
Jahr der Verteidigung:
2016
Sprache(n) :
Englisch
Schlagworte:
cell biology, endocytosis, implant
DDC Klassifikation :
570 Biowissenschaften, Biologie
URN :
urn:nbn:de:gbv:28-diss2016-0099-5
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00001785
erstellt am:
2016-08-12
zuletzt geändert am:
2018-06-30
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