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übersetzter Titel
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(I) Expression studies of differenciation-associated transcripts in sorted bovine trophoblast cells and (II) comparative analyses of tissue- and species-specific usage of the CYP19A1 promoter P1.5/2 of cattle and sheep |
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übersetzte Zusammenfassung
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In this work, a methodical protocol for sorting uninucleated trophoblast cells (UTC) and trophoblast giant cells (TGC) originating from the bovine placenta, was established. Based on the gene expression profiles of UTC and TGC, different expressed genes and associated biological functions could be identified. Additionally, the so far controversially discussed localization of the estrogen specific sulfotransferase 1E1 was resolved. The specific usage of the CYP19A1 promotor P1.5/2 of cattle and sheep could not be attributed to cis-elements or a different positioning of nucleosomes. |
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Schlagworte: |
Rinderplazenta, Reproduktion, Transkriptomanalyse, Trophoblastriesenzellen, SULT1E1, Promotoranalyse |
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DDC Klassifikation : |
570 Biowissenschaften, Biologie |
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