Jaime Trevin̂o,  Diego A.

Selective oxidation of C16 macrocyclic diene to epoxides and ketones

Rostock : Universität , 2017

https://doi.org/10.18453/rosdok_id00002353

http://purl.uni-rostock.de/rosdok/id00002353

Abstract:

In the present work, two approaches were followed in the oxidation of the macrocyclic diene 1,9-cyclohexadecadiene. Firstly, an epoxidation using hydrogen peroxide as oxidant was revised. A set of precursors used to form the peroxotungstophosphate active catalyst and a set of phase transfer catalyst were screened. The conversion and selectivity to the target epoxide varied pending on the precursor and PTC of choice. Secondly, a Wacker-type oxidation was done using different palladium complexes. Among them, a specific type of complexes showed a higher selectivity to the target ketone.

Dissertation Open Access