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Perdomo Rivera,  Rodisnel

Synthesis of functionalized pyridines and quinolines by palladium-catalyzed cross-coupling reactions

Rostock : Universität , 2018

https://doi.org/10.18453/rosdok_id00002513

http://purl.uni-rostock.de/rosdok/id00002513

This thesis deals with the functionalization of pentahalogenated pyridines and dihalogenated quinolines through palladium catalyzed cross coupling reactions. This includes the chemo-selective arylation and alkynylation of 4-bromo-2,3,5-trichloro-6-iodopyridine using Suzuki and Sonogashira reactions. The chemo-selective arylation of 4,6-dihalogenated-2-(trifluoromethyl)quinoline by Suzuki reaction was studied. Besides, the synthesis of indolo [2,3-c]quinolines was studied by sequential chemo-selective Suzuki reaction followed by double C-N coupling starting from 3-bromo-4-iodoquinoline.

Dissertation Open Access


Einrichtung :
Mathematisch-Naturwissenschaftliche Fakultät
Gutachter :
Langer,  Peter
Schmidt,  Bernd
Sprache(n) :
Englisch
DDC Klassifikation :
540 Chemie
URN :
urn:nbn:de:gbv:28-rosdok_id00002513-0
Persistente URL:
http://purl.uni-rostock.de/rosdok/id00002513
erstellt am:
2019-08-13
zuletzt geändert am:
2019-08-13
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