mycoreobjectrosdok_disshab_0000000056rosdok_disshab_0000000056rosdokdisshabrosdok_derivate_00000034732023-08-08T10:00:11.028Z2008-06-27T14:32:03.113Zadministratorpublished1rosdok_derivate_0000003473truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00000318570661501MODS updated during RosDok migration in June 2021DissertationHochschulschrift135691915EikHoffmann1976-VerfasserInautThe influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesenPD Dr.Sergei A.KuznetsovAkademischeR BetreuerIndgsProf.AlbertHaasAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000318http://purl.uni-rostock.de/rosdok/id00000318urn:nbn:de:gbv:28-diss2008-0050-9570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2007monographic20082007Universitätsbibliothek RostockRostock20082008Phagocytosis, the cellular uptake of particles and pathogens, is an essential function of the innate immune response. In this study, latex beads conjugated to immunoglobulin G, bacterial lipopolysaccharides, mannan or avidin were used to induce the internalization via different phagocytic receptors. Analysis of uptake and maturation of phagosomes, their proteomes as well as of macrophage gene expression during phagocytosis demonstrated that receptor-ligand interactions at the cell surface trigger a specfic signaling 'signature', which contributes to the intracellular fate of phagosomes.PhagozytoseMakrophageRezeptorUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000318doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:570SDNB:570570 Biowissenschaften, Biologie570 Life scienceinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.mnfinstitution:unirostock.mnfMathematisch-Naturwissenschaftliche FakultätFaculty of Mathematics and Natural SciencesUniversität Rostock. Mathematisch-Naturwissenschaftliche FakultätMathematisch-Natur-<br />wissenschaftliche FakultätUni.Rostock.Fakultaet.MNFhttp://d-nb.info/gnd/2147083-2accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/The influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesThe influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesgnd:135691915gnd:2147083-2gnd:135691915gnd:2147083-2rosdok_disshab_0000000056-d822917e39gnd:135691915Eik HoffmannEik Hoffmannrosdok_disshab_0000000056-d822917e60PD Dr. Sergei A. KuznetsovPD Dr. Sergei A. Kuznetsovrosdok_disshab_0000000056-d822917e72Prof. Albert HaasProf. Albert Haasrosdok_disshab_0000000056-d822917e84gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätEik HoffmannPD Dr. Sergei A. KuznetsovProf. Albert HaasUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätEik HoffmannPD Dr. Sergei A. KuznetsovProf. Albert HaasUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätEik HoffmannRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000318http://purl.uni-rostock.de/rosdok/id00000318urn:nbn:de:gbv:28-diss2008-0050-9PhagozytoseMakrophageRezeptorPhagocytosis, the cellular uptake of particles and pathogens, is an essential function of the innate immune response. In this study, latex beads conjugated to immunoglobulin G, bacterial lipopolysaccharides, mannan or avidin were used to induce the internalization via different phagocytic receptors. Analysis of uptake and maturation of phagosomes, their proteomes as well as of macrophage gene expression during phagocytosis demonstrated that receptor-ligand interactions at the cell surface trigger a specfic signaling 'signature', which contributes to the intracellular fate of phagosomes.20072007epub.dissertation1 Dissertation_Hoffmann_2008.pdf 14486241 39c76db61509cbddabf1e6f91a819e01 rosdok/id00000318570661501MODS updated during RosDok migration in June 2021DissertationHochschulschrift135691915EikHoffmann1976-VerfasserInautThe influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesenPD Dr.Sergei A.KuznetsovAkademischeR BetreuerIndgsProf.AlbertHaasAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000318http://purl.uni-rostock.de/rosdok/id00000318urn:nbn:de:gbv:28-diss2008-0050-9570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2007monographic20082007Universitätsbibliothek RostockRostock20082008Phagocytosis, the cellular uptake of particles and pathogens, is an essential function of the innate immune response. In this study, latex beads conjugated to immunoglobulin G, bacterial lipopolysaccharides, mannan or avidin were used to induce the internalization via different phagocytic receptors. Analysis of uptake and maturation of phagosomes, their proteomes as well as of macrophage gene expression during phagocytosis demonstrated that receptor-ligand interactions at the cell surface trigger a specfic signaling 'signature', which contributes to the intracellular fate of phagosomes.PhagozytoseMakrophageRezeptorUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000318 2008-06-27T14:32:03.113Z 2023-08-08T10:00:11.028Z 2023-08-18T10:00:11.032Z {"identifier":"rosdok/id00000318","type":"local_id","additional":"","service":"MCRLocalID","created":"2018-06-30T12:32:11.734Z"} {"identifier":"http://purl.uni-rostock.de/rosdok/id00000318","type":"purl","additional":"","service":"RosDokPURL","created":"2018-06-30T12:32:11.928Z","registered":"2018-06-30T12:32:11.928Z"} {"identifier":"10.18453/rosdok_id00000318","type":"doi","additional":"","service":"RosDokDOI","created":"2018-06-30T12:32:13.239Z","registered":"2018-06-30T12:32:13.239Z"} {"identifier":"urn:nbn:de:gbv:28-diss2008-0050-9","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2018-06-30T12:32:11.739Z","registered":"2008-06-28T02:27:02.000Z"} administratorfulltextfile/rosdok_disshab_0000000056/rosdok_derivate_0000003473/Dissertation_Hoffmann_2008.pdfThe influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesThe influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesgnd:135691915gnd:2147083-2gnd:135691915gnd:2147083-2rosdok_disshab_0000000056-d822917e39gnd:135691915Eik HoffmannEik Hoffmannrosdok_disshab_0000000056-d822917e60PD Dr. Sergei A. KuznetsovPD Dr. Sergei A. Kuznetsovrosdok_disshab_0000000056-d822917e72Prof. Albert HaasProf. Albert Haasrosdok_disshab_0000000056-d822917e84gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätEik HoffmannPD Dr. Sergei A. KuznetsovProf. Albert HaasUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätEik HoffmannPD Dr. Sergei A. KuznetsovProf. Albert HaasUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätEik HoffmannRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000318http://purl.uni-rostock.de/rosdok/id00000318urn:nbn:de:gbv:28-diss2008-0050-9PhagozytoseMakrophageRezeptorPhagocytosis, the cellular uptake of particles and pathogens, is an essential function of the innate immune response. In this study, latex beads conjugated to immunoglobulin G, bacterial lipopolysaccharides, mannan or avidin were used to induce the internalization via different phagocytic receptors. Analysis of uptake and maturation of phagosomes, their proteomes as well as of macrophage gene expression during phagocytosis demonstrated that receptor-ligand interactions at the cell surface trigger a specfic signaling 'signature', which contributes to the intracellular fate of phagosomes.20072007[xslt]Saxonrosdok/id00000318https://purl.uni-rostock.de/rosdok/id0000031857066150110.18453/rosdok_id00000318urn:nbn:de:gbv:28-diss2008-0050-9Eik HoffmannHoffmann EikThe influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesDissertationdoctoral thesisUniversität Rostock, 2007Phagocytosis, the cellular uptake of particles and pathogens, is an essential function of the innate immune response. In this study, latex beads conjugated to immunoglobulin G, bacterial lipopolysaccharides, mannan or avidin were used to induce the internalization via different phagocytic receptors.…Eik HoffmannThe influence of receptor-ligand interactions on gene expression and phagosome functions in mouse macrophagesUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000318135691915EikHoffmann1976-VerfasserInautPD Dr.Sergei A.KuznetsovAkademischeR BetreuerIndgsProf.AlbertHaasAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00000318[purl]http://purl.uni-rostock.de/rosdok/id00000318[urn]urn:nbn:de:gbv:28-diss2008-0050-9open_access20072007epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:570institution:unirostock.mnfstate:published