mycoreobjectrosdok_disshab_0000000102rosdok_disshab_0000000102rosdokdisshabrosdok_derivate_00000036342023-08-08T10:00:22.783Z2008-10-29T16:23:16.102Zadministratorpublished1rosdok_derivate_0000003634truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00000362585095019MODS updated during RosDok migration in June 2021DissertationHochschulschrift136535313KarolinKrüger1981-VerfasserInautSynthesis of Biologically Active N-Heterocycles and Amines via Catalytic Hydroamination of AlkynesenProf. Dr.MatthiasBellerAkademischeR BetreuerIndgsProf. Dr.PeterLangerAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000362http://purl.uni-rostock.de/rosdok/id00000362urn:nbn:de:gbv:28-diss2008-0096-0540 ChemieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2008monographic20082008Universitätsbibliothek RostockRostock20082008This thesis presents new syntheses of N-heterocycles and amines. Building up on our prior studies in titanium-catalyzed hydroamination of alkynes we discovered zinc salts as new hydroamination catalysts. Zinc chloride and zinc triflate were successfully applied in the intermolecular hydroamination of terminal alkynes for the synthesis of various substituted indole derivatives, pyrazolines and pyrazoles, pyridazinones as well as amines. Additional functionalization reactions on special synthesized indole structures lead to pharmaceutically and biologically interesting substances.indolehydroaminationzincUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000362doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:540SDNB:540540 Chemie540 Chemistry & allied sciencesinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.mnfinstitution:unirostock.mnfMathematisch-Naturwissenschaftliche FakultätFaculty of Mathematics and Natural SciencesUniversität Rostock. 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Building up on our prior studies in titanium-catalyzed hydroamination of alkynes we discovered zinc salts as new hydroamination catalysts. Zinc chloride and zinc triflate were successfully applied in the intermolecular hydroamination of terminal alkynes for the synthesis of various substituted indole derivatives, pyrazolines and pyrazoles, pyridazinones as well as amines. Additional functionalization reactions on special synthesized indole structures lead to pharmaceutically and biologically interesting substances.20082008epub.dissertation1 Dissertation_Krueger_2008.pdf 1760657 072069ccd16d7e9d26fcbcbe108961a0 rosdok/id00000362585095019MODS updated during RosDok migration in June 2021DissertationHochschulschrift136535313KarolinKrüger1981-VerfasserInautSynthesis of Biologically Active N-Heterocycles and Amines via Catalytic Hydroamination of AlkynesenProf. Dr.MatthiasBellerAkademischeR BetreuerIndgsProf. Dr.PeterLangerAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000362http://purl.uni-rostock.de/rosdok/id00000362urn:nbn:de:gbv:28-diss2008-0096-0540 ChemieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2008monographic20082008Universitätsbibliothek RostockRostock20082008This thesis presents new syntheses of N-heterocycles and amines. Building up on our prior studies in titanium-catalyzed hydroamination of alkynes we discovered zinc salts as new hydroamination catalysts. Zinc chloride and zinc triflate were successfully applied in the intermolecular hydroamination of terminal alkynes for the synthesis of various substituted indole derivatives, pyrazolines and pyrazoles, pyridazinones as well as amines. Additional functionalization reactions on special synthesized indole structures lead to pharmaceutically and biologically interesting substances.indolehydroaminationzincUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000362 2008-10-29T16:23:16.102Z 2023-08-08T10:00:22.783Z 2023-08-18T10:00:22.787Z {"identifier":"rosdok/id00000362","type":"local_id","additional":"","service":"MCRLocalID","created":"2018-06-30T12:33:56.083Z"} {"identifier":"http://purl.uni-rostock.de/rosdok/id00000362","type":"purl","additional":"","service":"RosDokPURL","created":"2018-06-30T12:33:56.272Z","registered":"2018-06-30T12:33:56.272Z"} {"identifier":"10.18453/rosdok_id00000362","type":"doi","additional":"","service":"RosDokDOI","created":"2018-06-30T12:33:57.624Z","registered":"2018-06-30T12:33:57.624Z"} {"identifier":"urn:nbn:de:gbv:28-diss2008-0096-0","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2018-06-30T12:33:56.087Z","registered":"2008-11-20T03:17:17.870Z"} administratorfulltextfile/rosdok_disshab_0000000102/rosdok_derivate_0000003634/Dissertation_Krueger_2008.pdfSynthesis of Biologically Active N-Heterocycles and Amines via Catalytic Hydroamination of AlkynesSynthesis of Biologically Active N-Heterocycles and Amines via Catalytic Hydroamination of Alkynesgnd:136535313gnd:2147083-2gnd:136535313gnd:2147083-2rosdok_disshab_0000000102-d2476406e39gnd:136535313Karolin KrügerKarolin Krügerrosdok_disshab_0000000102-d2476406e60Prof. Dr. Matthias BellerProf. Dr. Matthias Bellerrosdok_disshab_0000000102-d2476406e72Prof. Dr. Peter LangerProf. Dr. Peter Langerrosdok_disshab_0000000102-d2476406e84gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätKarolin KrügerProf. Dr. Matthias BellerProf. Dr. Peter LangerUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätKarolin KrügerProf. Dr. Matthias BellerProf. Dr. Peter LangerUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätKarolin KrügerRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000362http://purl.uni-rostock.de/rosdok/id00000362urn:nbn:de:gbv:28-diss2008-0096-0indolehydroaminationzincThis thesis presents new syntheses of N-heterocycles and amines. Building up on our prior studies in titanium-catalyzed hydroamination of alkynes we discovered zinc salts as new hydroamination catalysts. Zinc chloride and zinc triflate were successfully applied in the intermolecular hydroamination of terminal alkynes for the synthesis of various substituted indole derivatives, pyrazolines and pyrazoles, pyridazinones as well as amines. Additional functionalization reactions on special synthesized indole structures lead to pharmaceutically and biologically interesting substances.20082008[xslt]Saxonrosdok/id00000362https://purl.uni-rostock.de/rosdok/id0000036258509501910.18453/rosdok_id00000362urn:nbn:de:gbv:28-diss2008-0096-0Karolin KrügerKrüger KarolinSynthesis of Biologically Active N-Heterocycles and Amines via Catalytic Hydroamination of AlkynesDissertationdoctoral thesisUniversität Rostock, 2008This thesis presents new syntheses of N-heterocycles and amines. Building up on our prior studies in titanium-catalyzed hydroamination of alkynes we discovered zinc salts as new hydroamination catalysts. Zinc chloride and zinc triflate were successfully applied in the intermolecular hydroamination…Karolin KrügerSynthesis of Biologically Active N-Heterocycles and Amines via Catalytic Hydroamination of AlkynesUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000362136535313KarolinKrüger1981-VerfasserInautProf. Dr.MatthiasBellerAkademischeR BetreuerIndgsProf. Dr.PeterLangerAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00000362[purl]http://purl.uni-rostock.de/rosdok/id00000362[urn]urn:nbn:de:gbv:28-diss2008-0096-0open_access20082008epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:540institution:unirostock.mnfstate:published