mycoreobjectrosdok_disshab_0000000298rosdok_disshab_0000000298rosdokdisshabrosdok_derivate_00000039802023-08-08T10:01:10.938Z2010-04-21T10:34:34.963Zadministratorpublished1rosdok_derivate_0000003980truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00000535624016218MODS updated during RosDok migration in June 2021DissertationHochschulschrift139069127SylvioTetzlaff1977-VerfasserInautIdentification and analysis of functional candidate genes for the inverted teat defect in pigsenProf. Dr.ReinhardSchröderAkademischeR BetreuerIndgsProf. Dr.KlausWimmersAkademischeR BetreuerIndgsProf. Dr.KarlSchellanderAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000535http://purl.uni-rostock.de/rosdok/id00000535urn:nbn:de:gbv:28-diss2009-0154-1590 Tiere (Zoologie)570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2009monographic20092009Universitätsbibliothek RostockRostock20102010PTHR1 and LEF1 were analyzed as functional candidate genes for the inverted teat defect in pigs. SNP in both genes could be shown as significantly associated with inverted teats. QTL analyses revealed significant QTL on twelve chromosomes in an experimental and five chromosomes in a commercial pig population. That enabled the information about novel positional candidate genes. Adjacent microarray analyses of epithelial and mesenchymal teat tissues of affected and non-affected animals offered differentially regulated genes. Constitutive quantitative real-time analyses of FGFR2, GHR, HGF, PDGFA, PDGFRA, PDGFB and VEGF revealed significant differential expressions in the compared tissues.inherited disorderliability traitsexpression profileQTLfamily based associationUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000535doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:590SDNB:590590 Tiere (Zoologie)590 Zoological sciencesSDNB:570SDNB:570570 Biowissenschaften, Biologie570 Life scienceinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.mnfinstitution:unirostock.mnfMathematisch-Naturwissenschaftliche FakultätFaculty of Mathematics and Natural SciencesUniversität Rostock. Mathematisch-Naturwissenschaftliche FakultätMathematisch-Natur-<br />wissenschaftliche FakultätUni.Rostock.Fakultaet.MNFhttp://d-nb.info/gnd/2147083-2accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/Identification and analysis of functional candidate genes for the inverted teat defect in pigsIdentification and analysis of functional candidate genes for the inverted teat defect in pigsgnd:139069127gnd:2147083-2gnd:139069127gnd:2147083-2rosdok_disshab_0000000298-d1482433e39gnd:139069127Sylvio TetzlaffSylvio Tetzlaffrosdok_disshab_0000000298-d1482433e60Prof. Dr. Reinhard SchröderProf. Dr. Reinhard Schröderrosdok_disshab_0000000298-d1482433e72Prof. Dr. Klaus WimmersProf. Dr. Klaus Wimmersrosdok_disshab_0000000298-d1482433e84Prof. Dr. Karl SchellanderProf. Dr. Karl Schellanderrosdok_disshab_0000000298-d1482433e97gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSylvio TetzlaffProf. Dr. Reinhard SchröderProf. Dr. Klaus WimmersProf. Dr. Karl SchellanderUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSylvio TetzlaffProf. Dr. Reinhard SchröderProf. Dr. Klaus WimmersProf. Dr. Karl SchellanderUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSylvio TetzlaffRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000535http://purl.uni-rostock.de/rosdok/id00000535urn:nbn:de:gbv:28-diss2009-0154-1inherited disorderliability traitsexpression profileQTLfamily based associationPTHR1 and LEF1 were analyzed as functional candidate genes for the inverted teat defect in pigs. SNP in both genes could be shown as significantly associated with inverted teats. QTL analyses revealed significant QTL on twelve chromosomes in an experimental and five chromosomes in a commercial pig population. That enabled the information about novel positional candidate genes. Adjacent microarray analyses of epithelial and mesenchymal teat tissues of affected and non-affected animals offered differentially regulated genes. Constitutive quantitative real-time analyses of FGFR2, GHR, HGF, PDGFA, PDGFRA, PDGFB and VEGF revealed significant differential expressions in the compared tissues.20092009epub.dissertation1 Dissertation_Tetzlaff_2009.pdf 2088494 6ecf5271fdee5dcfe9ff4eaac21f62d0 rosdok/id00000535624016218MODS updated during RosDok migration in June 2021DissertationHochschulschrift139069127SylvioTetzlaff1977-VerfasserInautIdentification and analysis of functional candidate genes for the inverted teat defect in pigsenProf. Dr.ReinhardSchröderAkademischeR BetreuerIndgsProf. Dr.KlausWimmersAkademischeR BetreuerIndgsProf. Dr.KarlSchellanderAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000535http://purl.uni-rostock.de/rosdok/id00000535urn:nbn:de:gbv:28-diss2009-0154-1590 Tiere (Zoologie)570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2009monographic20092009Universitätsbibliothek RostockRostock20102010PTHR1 and LEF1 were analyzed as functional candidate genes for the inverted teat defect in pigs. SNP in both genes could be shown as significantly associated with inverted teats. QTL analyses revealed significant QTL on twelve chromosomes in an experimental and five chromosomes in a commercial pig population. That enabled the information about novel positional candidate genes. Adjacent microarray analyses of epithelial and mesenchymal teat tissues of affected and non-affected animals offered differentially regulated genes. 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SNP in both genes could be shown as significantly associated with inverted teats. QTL analyses revealed significant QTL on twelve chromosomes in an experimental and five chromosomes in a commercial pig population. That enabled the information about novel positional candidate genes. Adjacent microarray analyses of epithelial and mesenchymal teat tissues of affected and non-affected animals offered differentially regulated genes. Constitutive quantitative real-time analyses of FGFR2, GHR, HGF, PDGFA, PDGFRA, PDGFB and VEGF revealed significant differential expressions in the compared tissues.20092009[xslt]Saxonrosdok/id00000535https://purl.uni-rostock.de/rosdok/id0000053562401621810.18453/rosdok_id00000535urn:nbn:de:gbv:28-diss2009-0154-1Sylvio TetzlaffTetzlaff SylvioIdentification and analysis of functional candidate genes for the inverted teat defect in pigsDissertationdoctoral thesisUniversität Rostock, 2009PTHR1 and LEF1 were analyzed as functional candidate genes for the inverted teat defect in pigs. SNP in both genes could be shown as significantly associated with inverted teats. QTL analyses revealed significant QTL on twelve chromosomes in an experimental and five chromosomes in a commercial pig…Sylvio TetzlaffIdentification and analysis of functional candidate genes for the inverted teat defect in pigsUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000535139069127SylvioTetzlaff1977-VerfasserInautProf. Dr.ReinhardSchröderAkademischeR BetreuerIndgsProf. Dr.KlausWimmersAkademischeR BetreuerIndgsProf. Dr.KarlSchellanderAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00000535[purl]http://purl.uni-rostock.de/rosdok/id00000535[urn]urn:nbn:de:gbv:28-diss2009-0154-1open_access20092009epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:590SDNB:570institution:unirostock.mnfstate:published