10.18453/rosdok_id00000764 Ahmad, Syed Furquan Syed Furquan Ahmad http://d-nb.info/gnd/143082981 Universität Rostock 2010 570 Life science 2010 en http://purl.uni-rostock.de/rosdok/id00000764 urn:nbn:de:gbv:28-diss2010-0189-0 In this study the recognition maps obtained by the simultaneous topography and recognition (TREC) imaging revealed that Fcγ receptors are distributed in micro-domains of sizes 4nm to 200nm. The fluorescent and electron-microscopy provided further evidence that these clusters are located within close proximity of mannose receptors. This pattern of distribution of FcγRs and MRs led to inhibition of the MR mediated mediated phagocytosis. The data presented in this thesis provide evidences of cross-talk between FcγR mediated and MR mediated phagocytosis.