mycoreobjectrosdok_disshab_0000000597rosdok_disshab_0000000597rosdokdisshabrosdok_derivate_00000045502023-08-08T10:02:26.130Z2012-03-13T12:14:52.389Zadministratorpublished1rosdok_derivate_0000004550truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00000801688404820MODS updated during RosDok migration in June 2021DissertationHochschulschrift143547151SaijoThomas1979-VerfasserInautPositive stranded RNA virusesDissecting the capsid of Hepatitis E and Chikungunya virusesenProf. Dr. med.StephanSchaeferAkademischeR BetreuerIndgsProf. Dr. rer. nat.HubertBahlAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000801http://purl.uni-rostock.de/rosdok/id00000801urn:nbn:de:gbv:28-diss2011-0024-4610 Medizin, Gesundheit570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2010monographic20112010Universitätsbibliothek RostockRostock20122012Capsid protein of two positive stranded RNA viruses, Hepatitis E virus (HEV) and Chikungunya virus (ChikV), were investigated. HEV was detected in swine serum collected in Germany. An infectious system for HEV was established and was used to check its egress. The requirement of various amino acid sequences for the autoproteolytic cleavage of ChikV capsid protease was investigated. I was also able to show that ChikV capsid is recognized by karyopherins and its export is mediated by CRM1 dependent nuclear export signal.capsidHEVChikVproteaseUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000801doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:610SDNB:610610 Medizin, Gesundheit610 Medical sciences MedicineSDNB:570SDNB:570570 Biowissenschaften, Biologie570 Life scienceinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.mnfinstitution:unirostock.mnfMathematisch-Naturwissenschaftliche FakultätFaculty of Mathematics and Natural SciencesUniversität Rostock. Mathematisch-Naturwissenschaftliche FakultätMathematisch-Natur-<br />wissenschaftliche FakultätUni.Rostock.Fakultaet.MNFhttp://d-nb.info/gnd/2147083-2accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/Positive stranded RNA virusesDissecting the capsid of Hepatitis E and Chikungunya virusesPositive stranded RNA virusesDissecting the capsid of Hepatitis E and Chikungunya virusesgnd:143547151gnd:2147083-2gnd:143547151gnd:2147083-2rosdok_disshab_0000000597-d2133857e39gnd:143547151Saijo ThomasSaijo Thomasrosdok_disshab_0000000597-d2133857e61Prof. Dr. med. Stephan SchaeferProf. Dr. med. Stephan Schaeferrosdok_disshab_0000000597-d2133857e73Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000000597-d2133857e85gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSaijo ThomasProf. Dr. med. Stephan SchaeferProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSaijo ThomasProf. Dr. med. Stephan SchaeferProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSaijo ThomasRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000801http://purl.uni-rostock.de/rosdok/id00000801urn:nbn:de:gbv:28-diss2011-0024-4capsidHEVChikVproteaseCapsid protein of two positive stranded RNA viruses, Hepatitis E virus (HEV) and Chikungunya virus (ChikV), were investigated. HEV was detected in swine serum collected in Germany. An infectious system for HEV was established and was used to check its egress. The requirement of various amino acid sequences for the autoproteolytic cleavage of ChikV capsid protease was investigated. I was also able to show that ChikV capsid is recognized by karyopherins and its export is mediated by CRM1 dependent nuclear export signal.20102010epub.dissertation1 Dissertation_Thomas_2011.pdf 6919834 4237e02f8bd20acad6fee7663baf4312 rosdok/id00000801688404820MODS updated during RosDok migration in June 2021DissertationHochschulschrift143547151SaijoThomas1979-VerfasserInautPositive stranded RNA virusesDissecting the capsid of Hepatitis E and Chikungunya virusesenProf. Dr. med.StephanSchaeferAkademischeR BetreuerIndgsProf. Dr. rer. nat.HubertBahlAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00000801http://purl.uni-rostock.de/rosdok/id00000801urn:nbn:de:gbv:28-diss2011-0024-4610 Medizin, Gesundheit570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2010monographic20112010Universitätsbibliothek RostockRostock20122012Capsid protein of two positive stranded RNA viruses, Hepatitis E virus (HEV) and Chikungunya virus (ChikV), were investigated. HEV was detected in swine serum collected in Germany. An infectious system for HEV was established and was used to check its egress. The requirement of various amino acid sequences for the autoproteolytic cleavage of ChikV capsid protease was investigated. I was also able to show that ChikV capsid is recognized by karyopherins and its export is mediated by CRM1 dependent nuclear export signal.capsidHEVChikVproteaseUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000801 2012-03-13T12:14:52.389Z 2023-08-08T10:02:26.130Z 2023-08-18T10:02:26.135Z {"identifier":"rosdok/id00000801","type":"local_id","additional":"","service":"MCRLocalID","created":"2018-06-30T12:49:50.011Z"} {"identifier":"http://purl.uni-rostock.de/rosdok/id00000801","type":"purl","additional":"","service":"RosDokPURL","created":"2018-06-30T12:49:50.197Z","registered":"2018-06-30T12:49:50.197Z"} {"identifier":"10.18453/rosdok_id00000801","type":"doi","additional":"","service":"RosDokDOI","created":"2018-06-30T12:49:51.486Z","registered":"2018-06-30T12:49:51.486Z"} {"identifier":"urn:nbn:de:gbv:28-diss2011-0024-4","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2018-06-30T12:49:50.016Z","registered":"2012-03-14T03:26:58.300Z"} administratorfulltextfile/rosdok_disshab_0000000597/rosdok_derivate_0000004550/Dissertation_Thomas_2011.pdfPositive stranded RNA virusesDissecting the capsid of Hepatitis E and Chikungunya virusesPositive stranded RNA virusesDissecting the capsid of Hepatitis E and Chikungunya virusesgnd:143547151gnd:2147083-2gnd:143547151gnd:2147083-2rosdok_disshab_0000000597-d2133857e39gnd:143547151Saijo ThomasSaijo Thomasrosdok_disshab_0000000597-d2133857e61Prof. Dr. med. Stephan SchaeferProf. Dr. med. Stephan Schaeferrosdok_disshab_0000000597-d2133857e73Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000000597-d2133857e85gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSaijo ThomasProf. Dr. med. Stephan SchaeferProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSaijo ThomasProf. Dr. med. Stephan SchaeferProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätSaijo ThomasRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000801http://purl.uni-rostock.de/rosdok/id00000801urn:nbn:de:gbv:28-diss2011-0024-4capsidHEVChikVproteaseCapsid protein of two positive stranded RNA viruses, Hepatitis E virus (HEV) and Chikungunya virus (ChikV), were investigated. HEV was detected in swine serum collected in Germany. An infectious system for HEV was established and was used to check its egress. The requirement of various amino acid sequences for the autoproteolytic cleavage of ChikV capsid protease was investigated. I was also able to show that ChikV capsid is recognized by karyopherins and its export is mediated by CRM1 dependent nuclear export signal.20102010[xslt]Saxonrosdok/id00000801https://purl.uni-rostock.de/rosdok/id0000080168840482010.18453/rosdok_id00000801urn:nbn:de:gbv:28-diss2011-0024-4Saijo ThomasThomas SaijoPositive stranded RNA viruses : Dissecting the capsid of Hepatitis E and Chikungunya virusesDissertationdoctoral thesisUniversität Rostock, 2010Capsid protein of two positive stranded RNA viruses, Hepatitis E virus (HEV) and Chikungunya virus (ChikV), were investigated. HEV was detected in swine serum collected in Germany. An infectious system for HEV was established and was used to check its egress. The requirement of various amino acid…Saijo ThomasPositive stranded RNA virusesDissecting the capsid of Hepatitis E and Chikungunya virusesUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000801143547151SaijoThomas1979-VerfasserInautProf. Dr. med.StephanSchaeferAkademischeR BetreuerIndgsProf. Dr. rer. nat.HubertBahlAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00000801[purl]http://purl.uni-rostock.de/rosdok/id00000801[urn]urn:nbn:de:gbv:28-diss2011-0024-4open_access20102010epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:610SDNB:570institution:unirostock.mnfstate:published