10.18453/rosdok_id00000823 John, Mathias Mathias John http://d-nb.info/gnd/143691279 Universität Rostock 2010 004 Data processing Computer sciences 2010 en http://purl.uni-rostock.de/rosdok/id00000823 urn:nbn:de:gbv:28-diss2011-0047-3 For cell-biological processes, it is the complex interaction of their biochemical components, affected by both stochastic and spatial considerations, that create the overall picture. Formal modeling provides a method to overcome the limits of experimental observation in the wet-lab by moving to the abstract world of the computer. The limits of the abstract world again depend on the modeling language used to describe the system under study. In this thesis, reaction constraints for the pi-calculus are proposed as a language for the stochastic and spatial modeling of cell-biological processes.