mycoreobjectrosdok_disshab_0000000627rosdok_disshab_0000000627rosdokdisshabrosdok_derivate_00000045782023-08-08T10:02:33.497Z2012-03-13T13:56:25.068Zadministratorpublished1rosdok_derivate_0000004578truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00000828688447341MODS updated during RosDok migration in June 2021DissertationHochschulschrift143715887Reham FaragEl-Kased1979-VerfasserInautNovel Mass Spectrometry-based Epitope Mapping Procedures of AutoantigensenProf. Dr.Michael O.GlockerAkademischeR BetreuerIndgsProf. Dr. med.MichaelShmittAkademischeR BetreuerIndgsProf. Dr.AndreasTholeyAkademischeR BetreuerIndgs1029510660Universität RostockUniversitätsmedizinGrad-verleihende Institutiondgg10.18453/rosdok_id00000828http://purl.uni-rostock.de/rosdok/id00000828urn:nbn:de:gbv:28-diss2011-0054-1610 Medizin, GesundheitUniversitätsmedizinfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2010monographic20112010Universitätsbibliothek RostockRostock20122012Preventive medicine for patients is to be realized from monitoring and management of early stage disease rather than from late stage treatment. Among the strategies of preventive medicine is the detection of prognostic and diagnostic protein signatures, in particular epitopes against which autoantibodies in blood plasma are directed during the progression of the disease. Recognizing such diseasespecific antibodies in patient screenings requires knowledge of the respective epitopes. In this work, novel mass spectrometry-based methodologies for epitope mapping of autoantigens are described.epitope mappingmass spectrometryautoantigenautoantibodUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000828doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:610SDNB:610610 Medizin, Gesundheit610 Medical sciences Medicineinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.umrinstitution:unirostock.umrUniversitätsmedizinUniversity MedicineUniversität Rostock. UniversitätsmedizinUniversitätsmedizinUni.Rostock.Fakultaet.MEDhttp://d-nb.info/gnd/1029510660accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/Novel Mass Spectrometry-based Epitope Mapping Procedures of AutoantigensNovel Mass Spectrometry-based Epitope Mapping Procedures of Autoantigensgnd:143715887gnd:1029510660gnd:143715887gnd:1029510660rosdok_disshab_0000000627-d4581057e39gnd:143715887Reham Farag El-KasedReham Farag El-Kasedrosdok_disshab_0000000627-d4581057e60Prof. Dr. Michael O. GlockerProf. Dr. Michael O. Glockerrosdok_disshab_0000000627-d4581057e72Prof. Dr. med. Michael ShmittProf. Dr. med. Michael Shmittrosdok_disshab_0000000627-d4581057e84Prof. Dr. Andreas TholeyProf. Dr. Andreas Tholeyrosdok_disshab_0000000627-d4581057e97gnd:1029510660Universität Rostock UniversitätsmedizinUniversität Rostock UniversitätsmedizinReham Farag El-KasedProf. Dr. Michael O. GlockerProf. Dr. med. Michael ShmittProf. Dr. Andreas TholeyUniversität Rostock UniversitätsmedizinReham Farag El-KasedProf. Dr. Michael O. GlockerProf. Dr. med. Michael ShmittProf. Dr. Andreas TholeyUniversität Rostock UniversitätsmedizinReham Farag El-KasedRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000828http://purl.uni-rostock.de/rosdok/id00000828urn:nbn:de:gbv:28-diss2011-0054-1epitope mappingmass spectrometryautoantigenautoantibodPreventive medicine for patients is to be realized from monitoring and management of early stage disease rather than from late stage treatment. Among the strategies of preventive medicine is the detection of prognostic and diagnostic protein signatures, in particular epitopes against which autoantibodies in blood plasma are directed during the progression of the disease. Recognizing such diseasespecific antibodies in patient screenings requires knowledge of the respective epitopes. In this work, novel mass spectrometry-based methodologies for epitope mapping of autoantigens are described.20102010epub.dissertation1 Dissertation_El-Kased_2011.pdf 4998407 e7ec0b8ef8d8ba4585d7b70a73a202b5 rosdok/id00000828688447341MODS updated during RosDok migration in June 2021DissertationHochschulschrift143715887Reham FaragEl-Kased1979-VerfasserInautNovel Mass Spectrometry-based Epitope Mapping Procedures of AutoantigensenProf. Dr.Michael O.GlockerAkademischeR BetreuerIndgsProf. Dr. med.MichaelShmittAkademischeR BetreuerIndgsProf. Dr.AndreasTholeyAkademischeR BetreuerIndgs1029510660Universität RostockUniversitätsmedizinGrad-verleihende Institutiondgg10.18453/rosdok_id00000828http://purl.uni-rostock.de/rosdok/id00000828urn:nbn:de:gbv:28-diss2011-0054-1610 Medizin, GesundheitUniversitätsmedizinfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2010monographic20112010Universitätsbibliothek RostockRostock20122012Preventive medicine for patients is to be realized from monitoring and management of early stage disease rather than from late stage treatment. Among the strategies of preventive medicine is the detection of prognostic and diagnostic protein signatures, in particular epitopes against which autoantibodies in blood plasma are directed during the progression of the disease. Recognizing such diseasespecific antibodies in patient screenings requires knowledge of the respective epitopes. In this work, novel mass spectrometry-based methodologies for epitope mapping of autoantigens are described.epitope mappingmass spectrometryautoantigenautoantibodUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000828 2012-03-13T13:56:25.068Z 2023-08-08T10:02:33.497Z 2023-08-18T10:02:33.501Z {"identifier":"rosdok/id00000828","type":"local_id","additional":"","service":"MCRLocalID","created":"2018-06-30T12:50:47.586Z"} {"identifier":"http://purl.uni-rostock.de/rosdok/id00000828","type":"purl","additional":"","service":"RosDokPURL","created":"2018-06-30T12:50:47.711Z","registered":"2018-06-30T12:50:47.711Z"} {"identifier":"10.18453/rosdok_id00000828","type":"doi","additional":"","service":"RosDokDOI","created":"2018-06-30T12:50:48.978Z","registered":"2018-06-30T12:50:48.978Z"} {"identifier":"urn:nbn:de:gbv:28-diss2011-0054-1","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2018-06-30T12:50:47.590Z","registered":"2012-03-14T03:26:59.217Z"} administratorfulltextfile/rosdok_disshab_0000000627/rosdok_derivate_0000004578/Dissertation_El-Kased_2011.pdfNovel Mass Spectrometry-based Epitope Mapping Procedures of AutoantigensNovel Mass Spectrometry-based Epitope Mapping Procedures of Autoantigensgnd:143715887gnd:1029510660gnd:143715887gnd:1029510660rosdok_disshab_0000000627-d4581057e39gnd:143715887Reham Farag El-KasedReham Farag El-Kasedrosdok_disshab_0000000627-d4581057e60Prof. Dr. Michael O. GlockerProf. Dr. Michael O. Glockerrosdok_disshab_0000000627-d4581057e72Prof. Dr. med. Michael ShmittProf. Dr. med. Michael Shmittrosdok_disshab_0000000627-d4581057e84Prof. Dr. Andreas TholeyProf. Dr. Andreas Tholeyrosdok_disshab_0000000627-d4581057e97gnd:1029510660Universität Rostock UniversitätsmedizinUniversität Rostock UniversitätsmedizinReham Farag El-KasedProf. Dr. Michael O. GlockerProf. Dr. med. Michael ShmittProf. Dr. Andreas TholeyUniversität Rostock UniversitätsmedizinReham Farag El-KasedProf. Dr. Michael O. GlockerProf. Dr. med. Michael ShmittProf. Dr. Andreas TholeyUniversität Rostock UniversitätsmedizinReham Farag El-KasedRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00000828http://purl.uni-rostock.de/rosdok/id00000828urn:nbn:de:gbv:28-diss2011-0054-1epitope mappingmass spectrometryautoantigenautoantibodPreventive medicine for patients is to be realized from monitoring and management of early stage disease rather than from late stage treatment. Among the strategies of preventive medicine is the detection of prognostic and diagnostic protein signatures, in particular epitopes against which autoantibodies in blood plasma are directed during the progression of the disease. Recognizing such diseasespecific antibodies in patient screenings requires knowledge of the respective epitopes. In this work, novel mass spectrometry-based methodologies for epitope mapping of autoantigens are described.20102010[xslt]Saxonrosdok/id00000828https://purl.uni-rostock.de/rosdok/id0000082868844734110.18453/rosdok_id00000828urn:nbn:de:gbv:28-diss2011-0054-1Reham Farag El-KasedEl-Kased Reham FaragNovel Mass Spectrometry-based Epitope Mapping Procedures of AutoantigensDissertationdoctoral thesisUniversität Rostock, 2010Preventive medicine for patients is to be realized from monitoring and management of early stage disease rather than from late stage treatment. Among the strategies of preventive medicine is the detection of prognostic and diagnostic protein signatures, in particular epitopes against which…Reham Farag El-KasedNovel Mass Spectrometry-based Epitope Mapping Procedures of AutoantigensUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00000828143715887Reham FaragEl-Kased1979-VerfasserInautProf. Dr.Michael O.GlockerAkademischeR BetreuerIndgsProf. Dr. med.MichaelShmittAkademischeR BetreuerIndgsProf. Dr.AndreasTholeyAkademischeR BetreuerIndgs1029510660Universität RostockUniversitätsmedizinGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00000828[purl]http://purl.uni-rostock.de/rosdok/id00000828[urn]urn:nbn:de:gbv:28-diss2011-0054-1open_access20102010epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:610institution:unirostock.umrstate:published