10.18453/rosdok_id00000897 Zhou, Shaolin Shaolin Zhou http://d-nb.info/gnd/1014975603 Universität Rostock 2011 540 Chemistry & allied sciences 2011 en http://purl.uni-rostock.de/rosdok/id00000897 urn:nbn:de:gbv:28-diss2011-0127-7 This thesis presents the study and development of new catalysts based on first row transition metals for the (asymmetric) reduction of different C=O and C=N bonds. An iron cluster catalyst with a chiral tetradentate P2N2 ligand was discovered to catalyze the asymmetric transfer hydrogenation of N-diphenylphosphinylketimines. Subsequently the combination of a chiral Brønsted acid with a well-defined Shvo type iron complex creates an active catalyst which could hydrogenate a variety of N-aryl ketimines to amines using molecular hydrogen. Finally, an iron cluster catalyst was discovered to catalyze the reduction of amides with inexpensive PMHS.