Synthesis of Functionalized Quinolines, Flavones, Coumarins, Naphthoates and Phthalates by Site-Selective Suzuki-Miyaura Cross-Coupling Reactions

10.18453/rosdok_id00001028 Eleya, Nadi Fakhry Nadi Fakhry Eleya http://d-nb.info/gnd/1025628063 Synthesis of Functionalized Quinolines, Flavones, Coumarins, Naphthoates and Phthalates by Site-Selective Suzuki-Miyaura Cross-Coupling Reactions Universität Rostock 2012 540 Chemistry & allied sciences 2012 en http://purl.uni-rostock.de/rosdok/id00001028 urn:nbn:de:gbv:28-diss2012-0067-9 This thesis includes regioselective palladium(0)-catalyzed Suzuki cross-coupling reactions of quinolines, flavones, coumarins, naphthaoates and phthalates. Suzuki cross-coupling reaction of 5,7-dibromo-8-(trifluoromethanesulfonyloxy)quinoline afforded arylated quinolines.The Suzuki reaction of the bis(triflates)of 5,7-dihydroxyflavone,4-methyl-5,7-dihydroxycoumarin,4-methyl-5,8-dihydroxycoumarin, ethyl 3,5-dihydroxy-2-naphthaoate and methyl 3,7-dihydroxy-2-naphthoate gave the corresponding arylated derivatives. The reaction of tetrabromophthalate with boronic acids gave tetraarylphthalates.