10.18453/rosdok_id00001350 Supe, Linda Linda Supe http://d-nb.info/gnd/1054016976 Universität Rostock 2014 540 Chemistry & allied sciences 2014 en http://purl.uni-rostock.de/rosdok/id00001350 urn:nbn:de:gbv:28-diss2014-0102-2 The work is devoted to study synthesis of 1H-pyrazolo[3,4-b]pyridin-3(2H)-ones with potential biological activity. 1H-pyrazolo[3,4-b]pyridin-3(2H)-one derived moieties were afforded using classical approaches involving [3+3] cyclocondensation of enamine fragment-containing heterocycle and bielectrophiles, inverse electron-demand Diels-Alder reaction, palladium-catalyzed C-C coupling reaction. N-nucleosides of purine analogues were synthesized using modified silyl Hilbert-Jones method. Scope and limitations of hydrogenation of pyridine ring of 1H-pyrazolo[3,4-b]pyridin-3(2H)-ones were studied.