mycoreobjectrosdok_disshab_0000001189rosdok_disshab_0000001189rosdokdisshabrosdok_derivate_00000149002023-08-08T10:05:02.383Z2014-07-31T11:31:37.919ZadministratoreditorDpublished1rosdok_derivate_0000014900truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00001368793903564MODS updated during RosDok migration in June 2021DissertationHochschulschrift1054099537YueZhang1982-VerfasserInautDevelopment and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoveryEntwicklung und Evaluation von biotechnologischen Techniken für myokardiale Angiogenese und funktionale Genesungen136129560Prof. Dr. med.GustavSteinhoffUniversität Rostock, Medizinische FakultätAkademischeR BetreuerIndgsProf. Dr.JanGimsaUniversität Rostock, Mathematisch-Naturwissenschaftliche FakultätAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Mathematisch-Naturwissenschaftliche FakultätAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00001368http://purl.uni-rostock.de/rosdok/id00001368urn:nbn:de:gbv:28-diss2014-0120-2570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2014monographic20142014Universitätsbibliothek RostockRostock20142014Myocardial infarction is an irreversible injury of the heart muscle leading to complex changes in ventricular construction. Hence, the reduction and repair of myocardial damage are great challenges in clinical research. The objective of the present work was the development of novel biomedical techniques for cardiac regeneration employing targeted gene transfer and biomaterial-based tissue engineering. Using a rat model of MI, the therapeutic effect of stable magnetic field-guided MNBs/AdhVEGF complexes was evaluated on the one hand and intracardiac matrigel injection on the other hand.myocardial infarctiontissue engineeringangiogenesisUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00001368doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:570SDNB:570570 Biowissenschaften, Biologie570 Life scienceinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.mnfinstitution:unirostock.mnfMathematisch-Naturwissenschaftliche FakultätFaculty of Mathematics and Natural SciencesUniversität Rostock. Mathematisch-Naturwissenschaftliche FakultätMathematisch-Natur-<br />wissenschaftliche FakultätUni.Rostock.Fakultaet.MNFhttp://d-nb.info/gnd/2147083-2accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/Development and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoveryEntwicklung und Evaluation von biotechnologischen Techniken für myokardiale Angiogenese und funktionale GenesungDevelopment and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoverygnd:1054099537gnd:136129560gnd:132475170gnd:2147083-2gnd:1054099537gnd:136129560gnd:132475170gnd:2147083-2rosdok_disshab_0000001189-d2324078e39gnd:1054099537Yue ZhangYue Zhangrosdok_disshab_0000001189-d2324078e62gnd:136129560Prof. Dr. med. Gustav SteinhoffProf. Dr. med. Gustav Steinhoffrosdok_disshab_0000001189-d2324078e77Prof. Dr. Jan GimsaProf. Dr. Jan Gimsarosdok_disshab_0000001189-d2324078e91gnd:132475170Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000001189-d2324078e106gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätYue ZhangProf. Dr. med. Gustav SteinhoffProf. Dr. Jan GimsaProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätYue ZhangProf. Dr. med. Gustav SteinhoffProf. Dr. Jan GimsaProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätYue ZhangRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001368http://purl.uni-rostock.de/rosdok/id00001368urn:nbn:de:gbv:28-diss2014-0120-2myocardial infarctiontissue engineeringangiogenesisMyocardial infarction is an irreversible injury of the heart muscle leading to complex changes in ventricular construction. Hence, the reduction and repair of myocardial damage are great challenges in clinical research. The objective of the present work was the development of novel biomedical techniques for cardiac regeneration employing targeted gene transfer and biomaterial-based tissue engineering. Using a rat model of MI, the therapeutic effect of stable magnetic field-guided MNBs/AdhVEGF complexes was evaluated on the one hand and intracardiac matrigel injection on the other hand.20142014epub.dissertation1 Dissertation_Zhang_2014.pdf 4098236 2467a56bc1a691d6c7afbda53c2e043f rosdok/id00001368793903564MODS updated during RosDok migration in June 2021DissertationHochschulschrift1054099537YueZhang1982-VerfasserInautDevelopment and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoveryEntwicklung und Evaluation von biotechnologischen Techniken für myokardiale Angiogenese und funktionale Genesungen136129560Prof. Dr. med.GustavSteinhoffUniversität Rostock, Medizinische FakultätAkademischeR BetreuerIndgsProf. Dr.JanGimsaUniversität Rostock, Mathematisch-Naturwissenschaftliche FakultätAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Mathematisch-Naturwissenschaftliche FakultätAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00001368http://purl.uni-rostock.de/rosdok/id00001368urn:nbn:de:gbv:28-diss2014-0120-2570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2014monographic20142014Universitätsbibliothek RostockRostock20142014Myocardial infarction is an irreversible injury of the heart muscle leading to complex changes in ventricular construction. Hence, the reduction and repair of myocardial damage are great challenges in clinical research. The objective of the present work was the development of novel biomedical techniques for cardiac regeneration employing targeted gene transfer and biomaterial-based tissue engineering. Using a rat model of MI, the therapeutic effect of stable magnetic field-guided MNBs/AdhVEGF complexes was evaluated on the one hand and intracardiac matrigel injection on the other hand.myocardial infarctiontissue engineeringangiogenesisUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00001368 2014-07-31T11:31:37.919Z 2023-08-08T10:05:02.383Z 2023-08-18T10:05:02.389Z editorD {"identifier":"rosdok/id00001368","type":"local_id","additional":"","service":"MCRLocalID","created":"2018-06-30T13:10:05.539Z"} {"identifier":"http://purl.uni-rostock.de/rosdok/id00001368","type":"purl","additional":"","service":"RosDokPURL","created":"2018-06-30T13:10:05.732Z","registered":"2018-06-30T13:10:05.732Z"} {"identifier":"10.18453/rosdok_id00001368","type":"doi","additional":"","service":"RosDokDOI","created":"2018-06-30T13:10:07.018Z","registered":"2018-06-30T13:10:07.018Z"} {"identifier":"urn:nbn:de:gbv:28-diss2014-0120-2","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2018-06-30T13:10:05.545Z","registered":"2014-08-22T02:21:05.667Z"} administratorfulltextfile/rosdok_disshab_0000001189/rosdok_derivate_0000014900/Dissertation_Zhang_2014.pdfDevelopment and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoveryEntwicklung und Evaluation von biotechnologischen Techniken für myokardiale Angiogenese und funktionale GenesungDevelopment and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoverygnd:1054099537gnd:136129560gnd:132475170gnd:2147083-2gnd:1054099537gnd:136129560gnd:132475170gnd:2147083-2rosdok_disshab_0000001189-d2324078e39gnd:1054099537Yue ZhangYue Zhangrosdok_disshab_0000001189-d2324078e62gnd:136129560Prof. Dr. med. Gustav SteinhoffProf. Dr. med. Gustav Steinhoffrosdok_disshab_0000001189-d2324078e77Prof. Dr. Jan GimsaProf. Dr. Jan Gimsarosdok_disshab_0000001189-d2324078e91gnd:132475170Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000001189-d2324078e106gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätYue ZhangProf. Dr. med. Gustav SteinhoffProf. Dr. Jan GimsaProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätYue ZhangProf. Dr. med. Gustav SteinhoffProf. Dr. Jan GimsaProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätYue ZhangRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001368http://purl.uni-rostock.de/rosdok/id00001368urn:nbn:de:gbv:28-diss2014-0120-2myocardial infarctiontissue engineeringangiogenesisMyocardial infarction is an irreversible injury of the heart muscle leading to complex changes in ventricular construction. Hence, the reduction and repair of myocardial damage are great challenges in clinical research. The objective of the present work was the development of novel biomedical techniques for cardiac regeneration employing targeted gene transfer and biomaterial-based tissue engineering. Using a rat model of MI, the therapeutic effect of stable magnetic field-guided MNBs/AdhVEGF complexes was evaluated on the one hand and intracardiac matrigel injection on the other hand.20142014[xslt]Saxonrosdok/id00001368https://purl.uni-rostock.de/rosdok/id0000136879390356410.18453/rosdok_id00001368urn:nbn:de:gbv:28-diss2014-0120-2Yue ZhangZhang YueDevelopment and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoveryDissertationdoctoral thesisUniversität Rostock, 2014Myocardial infarction is an irreversible injury of the heart muscle leading to complex changes in ventricular construction. Hence, the reduction and repair of myocardial damage are great challenges in clinical research. The objective of the present work was the development of novel biomedical…Yue ZhangDevelopment and evaluation of biotechnological techniques for myocardial angiogenesis and functional recoveryEntwicklung und Evaluation von biotechnologischen Techniken für myokardiale Angiogenese und funktionale GenesungUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id000013681054099537YueZhang1982-VerfasserInaut136129560Prof. Dr. med.GustavSteinhoffUniversität Rostock, Medizinische FakultätAkademischeR BetreuerIndgsProf. Dr.JanGimsaUniversität Rostock, Mathematisch-Naturwissenschaftliche FakultätAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Mathematisch-Naturwissenschaftliche FakultätAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00001368[purl]http://purl.uni-rostock.de/rosdok/id00001368[urn]urn:nbn:de:gbv:28-diss2014-0120-2open_access20142014epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:570institution:unirostock.mnfstate:published