mycoreobjectrosdok_disshab_0000001230rosdok_disshab_0000001230rosdokdisshabrosdok_derivate_00000149402023-08-08T10:05:15.003Z2014-09-15T11:35:11.437ZadministratoreditorDpublished1rosdok_derivate_0000014940truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00001409796848564MODS updated during RosDok migration in June 2021DissertationHochschulschrift1036251721ZiWang1983-VerfasserInautThe role of minimal nerve injury in a new animal model for CRPSen136319564Prof. Dr. med.BrigitteVollmarUniversität Rostock, Institut für Experimentelle ChirurgieAkademischeR BetreuerIndgs121015688Universität Rostock, Abteilung für Unfall- und WiederherstellungschirurgieGeorgGradlProf. Dr. med.AkademischeR BetreuerIndgsPD. Dr. med.RalphKayserUniversität Greifswald, Klinik für Orthopädie und Orthopädische ChirurgieAkademischeR BetreuerIndgs1029510660Universität RostockUniversitätsmedizinGrad-verleihende Institutiondgg10.18453/rosdok_id00001409http://purl.uni-rostock.de/rosdok/id00001409urn:nbn:de:gbv:28-diss2014-0161-0610 Medizin, GesundheitUniversitätsmedizinfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2014monographic20132014Universitätsbibliothek RostockRostock20142014Complex regional pain syndrome(CRPS) is a chronic neuropathic pain disease which typically develops in distal extremities after trauma. The mechanism of CRPS is still unknown. We combined a closed soft tissue trauma in the hindlimb of a rat and a minimal nerve injury in the ipsilateral sciatic nerve to establish a new animal model for CRPS. This model induced CRPS symptoms including pain, altered temperature, muscle edema, regional inflammation and muscle cell apoptosis. However, most of the symptoms disappeared within four weeks. This new model is not sufficient to induce an ongoing CRPS.complex regional pain syndromeclosed soft tissue traumapost traumatic painUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00001409doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:610SDNB:610610 Medizin, Gesundheit610 Medical sciences Medicineinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.umrinstitution:unirostock.umrUniversitätsmedizinUniversity MedicineUniversität Rostock. UniversitätsmedizinUniversitätsmedizinUni.Rostock.Fakultaet.MEDhttp://d-nb.info/gnd/1029510660accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/The role of minimal nerve injury in a new animal model for CRPSThe role of minimal nerve injury in a new animal model for CRPSgnd:1036251721gnd:136319564gnd:121015688gnd:1029510660gnd:1036251721gnd:136319564gnd:121015688gnd:1029510660rosdok_disshab_0000001230-d1109152e39gnd:1036251721Zi WangZi Wangrosdok_disshab_0000001230-d1109152e60gnd:136319564Prof. Dr. med. Brigitte VollmarProf. Dr. med. Brigitte Vollmarrosdok_disshab_0000001230-d1109152e75gnd:121015688Universität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg GradlUniversität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg Gradlrosdok_disshab_0000001230-d1109152e90PD. Dr. med. Ralph KayserPD. Dr. med. Ralph Kayserrosdok_disshab_0000001230-d1109152e104gnd:1029510660Universität Rostock UniversitätsmedizinUniversität Rostock UniversitätsmedizinZi WangProf. Dr. med. Brigitte VollmarUniversität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg GradlPD. Dr. med. Ralph KayserUniversität Rostock UniversitätsmedizinZi WangProf. Dr. med. Brigitte VollmarUniversität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg GradlPD. Dr. med. Ralph KayserUniversität Rostock UniversitätsmedizinZi WangRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001409http://purl.uni-rostock.de/rosdok/id00001409urn:nbn:de:gbv:28-diss2014-0161-0complex regional pain syndromeclosed soft tissue traumapost traumatic painComplex regional pain syndrome(CRPS) is a chronic neuropathic pain disease which typically develops in distal extremities after trauma. The mechanism of CRPS is still unknown. We combined a closed soft tissue trauma in the hindlimb of a rat and a minimal nerve injury in the ipsilateral sciatic nerve to establish a new animal model for CRPS. This model induced CRPS symptoms including pain, altered temperature, muscle edema, regional inflammation and muscle cell apoptosis. However, most of the symptoms disappeared within four weeks. This new model is not sufficient to induce an ongoing CRPS.20142014epub.dissertation1 Dissertation_Wang_2014.pdf 1745059 4c0026c9f5cedd2dedf41e3208a8b940 rosdok/id00001409796848564MODS updated during RosDok migration in June 2021DissertationHochschulschrift1036251721ZiWang1983-VerfasserInautThe role of minimal nerve injury in a new animal model for CRPSen136319564Prof. Dr. med.BrigitteVollmarUniversität Rostock, Institut für Experimentelle ChirurgieAkademischeR BetreuerIndgs121015688Universität Rostock, Abteilung für Unfall- und WiederherstellungschirurgieGeorgGradlProf. Dr. med.AkademischeR BetreuerIndgsPD. Dr. med.RalphKayserUniversität Greifswald, Klinik für Orthopädie und Orthopädische ChirurgieAkademischeR BetreuerIndgs1029510660Universität RostockUniversitätsmedizinGrad-verleihende Institutiondgg10.18453/rosdok_id00001409http://purl.uni-rostock.de/rosdok/id00001409urn:nbn:de:gbv:28-diss2014-0161-0610 Medizin, GesundheitUniversitätsmedizinfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2014monographic20132014Universitätsbibliothek RostockRostock20142014Complex regional pain syndrome(CRPS) is a chronic neuropathic pain disease which typically develops in distal extremities after trauma. The mechanism of CRPS is still unknown. We combined a closed soft tissue trauma in the hindlimb of a rat and a minimal nerve injury in the ipsilateral sciatic nerve to establish a new animal model for CRPS. This model induced CRPS symptoms including pain, altered temperature, muscle edema, regional inflammation and muscle cell apoptosis. However, most of the symptoms disappeared within four weeks. This new model is not sufficient to induce an ongoing CRPS.complex regional pain syndromeclosed soft tissue traumapost traumatic painUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00001409 2014-09-15T11:35:11.437Z 2023-08-08T10:05:15.003Z 2023-08-18T10:05:15.008Z editorD {"identifier":"rosdok/id00001409","type":"local_id","additional":"","service":"MCRLocalID","created":"2018-06-30T13:11:35.224Z"} {"identifier":"http://purl.uni-rostock.de/rosdok/id00001409","type":"purl","additional":"","service":"RosDokPURL","created":"2018-06-30T13:11:35.450Z","registered":"2018-06-30T13:11:35.450Z"} {"identifier":"10.18453/rosdok_id00001409","type":"doi","additional":"","service":"RosDokDOI","created":"2018-06-30T13:11:36.771Z","registered":"2018-06-30T13:11:36.771Z"} {"identifier":"urn:nbn:de:gbv:28-diss2014-0161-0","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2018-06-30T13:11:35.229Z","registered":"2014-09-18T02:17:05.137Z"} administratorfulltextfile/rosdok_disshab_0000001230/rosdok_derivate_0000014940/Dissertation_Wang_2014.pdfThe role of minimal nerve injury in a new animal model for CRPSThe role of minimal nerve injury in a new animal model for CRPSgnd:1036251721gnd:136319564gnd:121015688gnd:1029510660gnd:1036251721gnd:136319564gnd:121015688gnd:1029510660rosdok_disshab_0000001230-d1109152e39gnd:1036251721Zi WangZi Wangrosdok_disshab_0000001230-d1109152e60gnd:136319564Prof. Dr. med. Brigitte VollmarProf. Dr. med. Brigitte Vollmarrosdok_disshab_0000001230-d1109152e75gnd:121015688Universität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg GradlUniversität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg Gradlrosdok_disshab_0000001230-d1109152e90PD. Dr. med. Ralph KayserPD. Dr. med. Ralph Kayserrosdok_disshab_0000001230-d1109152e104gnd:1029510660Universität Rostock UniversitätsmedizinUniversität Rostock UniversitätsmedizinZi WangProf. Dr. med. Brigitte VollmarUniversität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg GradlPD. Dr. med. Ralph KayserUniversität Rostock UniversitätsmedizinZi WangProf. Dr. med. Brigitte VollmarUniversität Rostock, Abteilung für Unfall- und Wiederherstellungschirurgie Georg GradlPD. Dr. med. Ralph KayserUniversität Rostock UniversitätsmedizinZi WangRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001409http://purl.uni-rostock.de/rosdok/id00001409urn:nbn:de:gbv:28-diss2014-0161-0complex regional pain syndromeclosed soft tissue traumapost traumatic painComplex regional pain syndrome(CRPS) is a chronic neuropathic pain disease which typically develops in distal extremities after trauma. The mechanism of CRPS is still unknown. We combined a closed soft tissue trauma in the hindlimb of a rat and a minimal nerve injury in the ipsilateral sciatic nerve to establish a new animal model for CRPS. This model induced CRPS symptoms including pain, altered temperature, muscle edema, regional inflammation and muscle cell apoptosis. However, most of the symptoms disappeared within four weeks. This new model is not sufficient to induce an ongoing CRPS.20142014[xslt]Saxonrosdok/id00001409https://purl.uni-rostock.de/rosdok/id0000140979684856410.18453/rosdok_id00001409urn:nbn:de:gbv:28-diss2014-0161-0Zi WangWang ZiThe role of minimal nerve injury in a new animal model for CRPSDissertationdoctoral thesisUniversität Rostock, 2014Complex regional pain syndrome(CRPS) is a chronic neuropathic pain disease which typically develops in distal extremities after trauma. The mechanism of CRPS is still unknown. We combined a closed soft tissue trauma in the hindlimb of a rat and a minimal nerve injury in the ipsilateral sciatic…Zi WangThe role of minimal nerve injury in a new animal model for CRPSUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id000014091036251721ZiWang1983-VerfasserInaut136319564Prof. Dr. med.BrigitteVollmarUniversität Rostock, Institut für Experimentelle ChirurgieAkademischeR BetreuerIndgs121015688Universität Rostock, Abteilung für Unfall- und WiederherstellungschirurgieGeorgGradlProf. Dr. med.AkademischeR BetreuerIndgsPD. Dr. med.RalphKayserUniversität Greifswald, Klinik für Orthopädie und Orthopädische ChirurgieAkademischeR BetreuerIndgs1029510660Universität RostockUniversitätsmedizinGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00001409[purl]http://purl.uni-rostock.de/rosdok/id00001409[urn]urn:nbn:de:gbv:28-diss2014-0161-0open_access20142014epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:610institution:unirostock.umrstate:published