10.18453/rosdok_id00001536 Abbasi, Muhammad Shakeel Ahmed Muhammad Shakeel Ahmed Abbasi http://d-nb.info/gnd/1071809431 Universität Rostock 2015 540 Chemistry & allied sciences 2015 en http://purl.uni-rostock.de/rosdok/id00001536 urn:nbn:de:gbv:28-diss2015-0086-0 A simple and convenient domino cycloaromatization approach towards the synthesis of novel benzo[c]chromen-6-ones and benzo[c]chromenes by treatment of heterocyclic chlorovinyl-aldehydes with active methylene compounds has been developed. In another strategy novel biaryl lactones were prepared by Sonogashira cross-coupling and base catalyzed reactions of 4-chloro-2-oxo-2H-chromene-3-carbaldehyde with terminal alkynes and 1, 3-dicarbonyl compounds.Finally some heterocyclic chlorovinyl-aldehydes were treated with electron rich heterocyclic amines to afford novel heteroannulated pyridines.