10.18453/rosdok_id00001603 Kleeblatt, Juliane Juliane Kleeblatt http://d-nb.info/gnd/1075766761 Universität Rostock 2015 540 Chemistry & allied sciences 610 Medical sciences Medicine 2015 en http://purl.uni-rostock.de/rosdok/id00001603 urn:nbn:de:gbv:28-diss2015-0153-1 The present thesis describes a combination of pre-concentration technique needle trap device (NTD) and thermal-desorption in a photoionization time-of-flight mass spectrometer (PI-TOFMS) for analysis of gaseous organic compounds in complex gas mixtures. By variation of the adsorbent materials inside the needle trap and the variation of the ionization wavelengths (different photon energies), it is possible to measure various organic substances. Thus, the method is interesting and applicable for several analytical research fields (e.g. breath gas analysis).