mycoreobjectrosdok_disshab_0000001460rosdok_disshab_0000001460rosdokdisshabrosdok_derivate_00000328042023-08-08T10:06:26.517Z2015-12-07T14:27:43.724ZadministratoreditorDpublished1rosdok_derivate_0000032804truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id0000163984238586XMODS updated during RosDok migration in June 2021DissertationHochschulschrift1079150099FarahnazAsghari1978-VerfasserInautMolecular, immunological and genetic studies on murine autoimmune pancreatitisenProf. Dr. med.RobertJasterUniversität Rostock, Klinik für Innere Medizin II,Abteilung Gastroenterologie und EndokrinologieAkademischeR BetreuerIndgsProf. Dr.UlrikeGimsaUniversität Rostock, Leibniz-Institut für Nutztierbiologie,Institut für Verhaltensphysiologie, DummerstorfAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00001639http://purl.uni-rostock.de/rosdok/id00001639urn:nbn:de:gbv:28-diss2015-0189-6610 Medizin, Gesundheit570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2015monographic20152015Universitätsbibliothek RostockRostock20152015To identify susceptible regions of the genome(quantitative trait loci; QTLs)controlling Autoimmune pancreatitis in a mouse model of the disease, we established an advanced intercross line originating from three inbred mouse strains: MRL/MpJ,BXD2,NZM and wild derived strain Cast. The fourth generation of outbred intercross mice was characterized phenotypically by scoring histopathological changes of the pancreas and genotyped (Illumina, USA).Five QTLs, regulating the severity of AIP, were identified, which mapped to chromosomes 2,4,5 and 6(with Logarithmic P values varied from 3.2 to 5.4).Autoimmune Pankreatitisquantitative trait lociMRL/MpJ MouseUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00001639doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:610SDNB:610610 Medizin, Gesundheit610 Medical sciences MedicineSDNB:570SDNB:570570 Biowissenschaften, Biologie570 Life scienceinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.mnfinstitution:unirostock.mnfMathematisch-Naturwissenschaftliche FakultätFaculty of Mathematics and Natural SciencesUniversität Rostock. Mathematisch-Naturwissenschaftliche FakultätMathematisch-Natur-<br />wissenschaftliche FakultätUni.Rostock.Fakultaet.MNFhttp://d-nb.info/gnd/2147083-2accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/Molecular, immunological and genetic studies on murine autoimmune pancreatitisMolecular, immunological and genetic studies on murine autoimmune pancreatitisgnd:1079150099gnd:2147083-2gnd:1079150099gnd:2147083-2rosdok_disshab_0000001460-d198576e39gnd:1079150099Farahnaz AsghariFarahnaz Asgharirosdok_disshab_0000001460-d198576e60Prof. Dr. med. Robert JasterProf. Dr. med. Robert Jasterrosdok_disshab_0000001460-d198576e73Prof. Dr. Ulrike GimsaProf. Dr. Ulrike Gimsarosdok_disshab_0000001460-d198576e86gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätFarahnaz AsghariProf. Dr. med. Robert JasterProf. Dr. Ulrike GimsaUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätFarahnaz AsghariProf. Dr. med. Robert JasterProf. Dr. Ulrike GimsaUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätFarahnaz AsghariRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001639http://purl.uni-rostock.de/rosdok/id00001639urn:nbn:de:gbv:28-diss2015-0189-6Autoimmune Pankreatitisquantitative trait lociMRL/MpJ MouseTo identify susceptible regions of the genome(quantitative trait loci; QTLs)controlling Autoimmune pancreatitis in a mouse model of the disease, we established an advanced intercross line originating from three inbred mouse strains: MRL/MpJ,BXD2,NZM and wild derived strain Cast. The fourth generation of outbred intercross mice was characterized phenotypically by scoring histopathological changes of the pancreas and genotyped (Illumina, USA).Five QTLs, regulating the severity of AIP, were identified, which mapped to chromosomes 2,4,5 and 6(with Logarithmic P values varied from 3.2 to 5.4).20152015epub.dissertation1 Dissertation_Asghari_2015.pdf 7668914 24755f5ce77d0d2cbd9e9bc2999fcb23 rosdok/id0000163984238586XMODS updated during RosDok migration in June 2021DissertationHochschulschrift1079150099FarahnazAsghari1978-VerfasserInautMolecular, immunological and genetic studies on murine autoimmune pancreatitisenProf. Dr. med.RobertJasterUniversität Rostock, Klinik für Innere Medizin II,Abteilung Gastroenterologie und EndokrinologieAkademischeR BetreuerIndgsProf. Dr.UlrikeGimsaUniversität Rostock, Leibniz-Institut für Nutztierbiologie,Institut für Verhaltensphysiologie, DummerstorfAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00001639http://purl.uni-rostock.de/rosdok/id00001639urn:nbn:de:gbv:28-diss2015-0189-6610 Medizin, Gesundheit570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2015monographic20152015Universitätsbibliothek RostockRostock20152015To identify susceptible regions of the genome(quantitative trait loci; QTLs)controlling Autoimmune pancreatitis in a mouse model of the disease, we established an advanced intercross line originating from three inbred mouse strains: MRL/MpJ,BXD2,NZM and wild derived strain Cast. The fourth generation of outbred intercross mice was characterized phenotypically by scoring histopathological changes of the pancreas and genotyped (Illumina, USA).Five QTLs, regulating the severity of AIP, were identified, which mapped to chromosomes 2,4,5 and 6(with Logarithmic P values varied from 3.2 to 5.4).Autoimmune Pankreatitisquantitative trait lociMRL/MpJ MouseUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00001639 2015-12-07T14:27:43.724Z 2023-08-08T10:06:26.517Z 2023-08-18T10:06:26.522Z editorD {"identifier":"rosdok/id00001639","type":"local_id","additional":"","service":"MCRLocalID","created":"2018-06-30T13:19:41.677Z"} {"identifier":"http://purl.uni-rostock.de/rosdok/id00001639","type":"purl","additional":"","service":"RosDokPURL","created":"2018-06-30T13:19:41.809Z","registered":"2018-06-30T13:19:41.809Z"} {"identifier":"10.18453/rosdok_id00001639","type":"doi","additional":"","service":"RosDokDOI","created":"2018-06-30T13:19:43.224Z","registered":"2018-06-30T13:19:43.224Z"} {"identifier":"urn:nbn:de:gbv:28-diss2015-0189-6","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2018-06-30T13:19:41.683Z","registered":"2015-12-09T03:20:15.197Z"} administratorfulltextfile/rosdok_disshab_0000001460/rosdok_derivate_0000032804/Dissertation_Asghari_2015.pdfMolecular, immunological and genetic studies on murine autoimmune pancreatitisMolecular, immunological and genetic studies on murine autoimmune pancreatitisgnd:1079150099gnd:2147083-2gnd:1079150099gnd:2147083-2rosdok_disshab_0000001460-d198576e39gnd:1079150099Farahnaz AsghariFarahnaz Asgharirosdok_disshab_0000001460-d198576e60Prof. Dr. med. Robert JasterProf. Dr. med. Robert Jasterrosdok_disshab_0000001460-d198576e73Prof. Dr. Ulrike GimsaProf. Dr. Ulrike Gimsarosdok_disshab_0000001460-d198576e86gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätFarahnaz AsghariProf. Dr. med. Robert JasterProf. Dr. Ulrike GimsaUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätFarahnaz AsghariProf. Dr. med. Robert JasterProf. Dr. Ulrike GimsaUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätFarahnaz AsghariRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001639http://purl.uni-rostock.de/rosdok/id00001639urn:nbn:de:gbv:28-diss2015-0189-6Autoimmune Pankreatitisquantitative trait lociMRL/MpJ MouseTo identify susceptible regions of the genome(quantitative trait loci; QTLs)controlling Autoimmune pancreatitis in a mouse model of the disease, we established an advanced intercross line originating from three inbred mouse strains: MRL/MpJ,BXD2,NZM and wild derived strain Cast. The fourth generation of outbred intercross mice was characterized phenotypically by scoring histopathological changes of the pancreas and genotyped (Illumina, USA).Five QTLs, regulating the severity of AIP, were identified, which mapped to chromosomes 2,4,5 and 6(with Logarithmic P values varied from 3.2 to 5.4).20152015[xslt]Saxonrosdok/id00001639https://purl.uni-rostock.de/rosdok/id0000163984238586X10.18453/rosdok_id00001639urn:nbn:de:gbv:28-diss2015-0189-6Farahnaz AsghariAsghari FarahnazMolecular, immunological and genetic studies on murine autoimmune pancreatitisDissertationdoctoral thesisUniversität Rostock, 2015To identify susceptible regions of the genome(quantitative trait loci; QTLs)controlling Autoimmune pancreatitis in a mouse model of the disease, we established an advanced intercross line originating from three inbred mouse strains: MRL/MpJ,BXD2,NZM and wild derived strain Cast. The fourth…Farahnaz AsghariMolecular, immunological and genetic studies on murine autoimmune pancreatitisUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id000016391079150099FarahnazAsghari1978-VerfasserInautProf. Dr. med.RobertJasterUniversität Rostock, Klinik für Innere Medizin II,Abteilung Gastroenterologie und EndokrinologieAkademischeR BetreuerIndgsProf. Dr.UlrikeGimsaUniversität Rostock, Leibniz-Institut für Nutztierbiologie,Institut für Verhaltensphysiologie, DummerstorfAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00001639[purl]http://purl.uni-rostock.de/rosdok/id00001639[urn]urn:nbn:de:gbv:28-diss2015-0189-6open_access20152015epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:610SDNB:570institution:unirostock.mnfstate:published