mycoreobjectrosdok_disshab_0000001763rosdok_disshab_0000001763rosdokdisshabrosdok_derivate_00000372092023-08-08T10:08:07.681Z2017-07-19T11:33:48.458ZadministratoreditorDpublished1rosdok_derivate_0000037209truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id00001941894195999MODS updated during RosDok migration in June 2021DissertationHochschulschrift1136984550CathleenHieke1989-VerfasserInautOral bacteria, stem cells and neutrophils in vitroa model for periodontal infectionen114684618Prof. Dr. rer. nat.BerndKreikemeyerUniversität Rostock, Institut für Mikrobiologie, Virologie und HygieneAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Institut für Mikrobiologie, Virologie und HygieneAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00001941http://purl.uni-rostock.de/rosdok/id00001941urn:nbn:de:gbv:28-diss2017-0105-5570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2017monographic20172017Universitätsbibliothek RostockRostock20172017Periodontitis is a chronic inflammatory disease induced by bacteria from oral biofilms. Bacteria interact with host cells and can subsequently provoke activation of polymorphonuclear neutrophils (PMNs). In this study, an in vitro model was applied to investigate interactions between periodontal pathogens, i.e., P. intermedia, T. forsythia and P. gingivalis, human dental stem cells (hDFSCs) and PMNs. 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Mathematisch-Naturwissenschaftliche FakultätMathematisch-Natur-<br />wissenschaftliche FakultätUni.Rostock.Fakultaet.MNFhttp://d-nb.info/gnd/2147083-2accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/Oral bacteria, stem cells and neutrophils in vitroa model for periodontal infectionOral bacteria, stem cells and neutrophils in vitroa model for periodontal infectiongnd:1136984550gnd:114684618gnd:132475170gnd:2147083-2gnd:1136984550gnd:114684618gnd:132475170gnd:2147083-2rosdok_disshab_0000001763-d63231e39gnd:1136984550Cathleen HiekeCathleen Hiekerosdok_disshab_0000001763-d63231e61gnd:114684618Prof. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Bernd Kreikemeyerrosdok_disshab_0000001763-d63231e76gnd:132475170Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000001763-d63231e91gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätCathleen HiekeProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätCathleen HiekeProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätCathleen HiekeRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001941http://purl.uni-rostock.de/rosdok/id00001941urn:nbn:de:gbv:28-diss2017-0105-5microbial-host interactionpeptidylarginine deiminaseimmune modulationantimicrobial activityPeriodontitis is a chronic inflammatory disease induced by bacteria from oral biofilms. Bacteria interact with host cells and can subsequently provoke activation of polymorphonuclear neutrophils (PMNs). In this study, an in vitro model was applied to investigate interactions between periodontal pathogens, i.e., P. intermedia, T. forsythia and P. gingivalis, human dental stem cells (hDFSCs) and PMNs. 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Bacteria interact with host cells and can subsequently provoke activation of polymorphonuclear neutrophils (PMNs). In this study, an in vitro model was applied to investigate interactions between periodontal pathogens, i.e., P. intermedia, T. forsythia and P. gingivalis, human dental stem cells (hDFSCs) and PMNs. 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Bernd KreikemeyerProf. Dr. rer. nat. Bernd Kreikemeyerrosdok_disshab_0000001763-d63231e76gnd:132475170Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000001763-d63231e91gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätCathleen HiekeProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätCathleen HiekeProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätCathleen HiekeRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00001941http://purl.uni-rostock.de/rosdok/id00001941urn:nbn:de:gbv:28-diss2017-0105-5microbial-host interactionpeptidylarginine deiminaseimmune modulationantimicrobial activityPeriodontitis is a chronic inflammatory disease induced by bacteria from oral biofilms. Bacteria interact with host cells and can subsequently provoke activation of polymorphonuclear neutrophils (PMNs). In this study, an in vitro model was applied to investigate interactions between periodontal pathogens, i.e., P. intermedia, T. forsythia and P. gingivalis, human dental stem cells (hDFSCs) and PMNs. HDFSCs modulate immune activity of PMNs after infection with oral bacteria implying general suitability of hDFSCs in tissue regeneration strategies after tissue damage in periodontal infections.20172017[xslt]Saxonrosdok/id00001941https://purl.uni-rostock.de/rosdok/id0000194189419599910.18453/rosdok_id00001941urn:nbn:de:gbv:28-diss2017-0105-5Cathleen HiekeHieke CathleenOral bacteria, stem cells and neutrophils in vitro : a model for periodontal infectionDissertationdoctoral thesisUniversität Rostock, 2017Periodontitis is a chronic inflammatory disease induced by bacteria from oral biofilms. Bacteria interact with host cells and can subsequently provoke activation of polymorphonuclear neutrophils (PMNs). In this study, an in vitro model was applied to investigate interactions between periodontal…Cathleen HiekeOral bacteria, stem cells and neutrophils in vitroa model for periodontal infectionUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id000019411136984550CathleenHieke1989-VerfasserInaut114684618Prof. Dr. rer. nat.BerndKreikemeyerUniversität Rostock, Institut für Mikrobiologie, Virologie und HygieneAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Institut für Mikrobiologie, Virologie und HygieneAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00001941[purl]http://purl.uni-rostock.de/rosdok/id00001941[urn]urn:nbn:de:gbv:28-diss2017-0105-5open_access20172017epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:570institution:unirostock.mnfstate:published