mycoreobjectrosdok_disshab_0000001859rosdok_disshab_0000001859rosdokdisshabrosdok_derivate_00000384582023-08-08T10:08:40.806Z2018-03-21T15:43:01.183ZadministratoreditorDpublished1rosdok_derivate_0000038458truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id000020371016258844MODS updated during RosDok migration in June 2021DissertationHochschulschrift1154729249Thomas JosefDauben1989-VerfasserInautEstablishment of a novel in vitro implant infection modeleffects of electrical stimulation on staphylococci using alternating currenten114684618Prof. Dr. rer. nat.BerndKreikemeyerUniversitätsmedizin Rostock, Institut für Medizinische Mikrobiologie, Virologie und HygieneAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Institut für BiowissenschaftenAkademischeR BetreuerIndgs133499847Prof. Dr. med.RainerBaderUniversitätsmedizin Rostock, Orthopädische Klinik und Poliklinik, Forschungslabor für Biomechanik und ImplantattechnologieAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00002037http://purl.uni-rostock.de/rosdok/id00002037urn:nbn:de:gbv:28-diss2018-0031-8570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2018monographic20182018Universitätsbibliothek RostockRostock20182018An in vitro system for electrical stimulation of cells and bacteria was developed. Stimulation of cells and bacteria can be conducted under similar conditions. Prior to experiments, numerical simulations were performed. Methods for evaluation of effects were established. Stimulation showed significant effects on bacterial growth and biofilm mass production. Following stimulation, changes in extracellular DNA amounts were detected. In co-culture, stimulation led to increased CFU/ml S. epidermidis in supernatants, on and into MG63 cells on electrode surfaces and chamber bottom.biofilmosteoblastbacterial growthUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00002037doctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisrfc5646:enrfc5646:enEnglischEnglishengengSDNB:570SDNB:570570 Biowissenschaften, Biologie570 Life scienceinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.mnfinstitution:unirostock.mnfMathematisch-Naturwissenschaftliche FakultätFaculty of Mathematics and Natural SciencesUniversität Rostock. Mathematisch-Naturwissenschaftliche FakultätMathematisch-Natur-<br />wissenschaftliche FakultätUni.Rostock.Fakultaet.MNFhttp://d-nb.info/gnd/2147083-2accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2licenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/Establishment of a novel in vitro implant infection modeleffects of electrical stimulation on staphylococci using alternating currentEstablishment of a novel in vitro implant infection modeleffects of electrical stimulation on staphylococci using alternating currentgnd:1154729249gnd:114684618gnd:132475170gnd:133499847gnd:2147083-2gnd:1154729249gnd:114684618gnd:132475170gnd:133499847gnd:2147083-2rosdok_disshab_0000001859-d1493164e39gnd:1154729249Thomas Josef DaubenThomas Josef Daubenrosdok_disshab_0000001859-d1493164e61gnd:114684618Prof. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Bernd Kreikemeyerrosdok_disshab_0000001859-d1493164e76gnd:132475170Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000001859-d1493164e91gnd:133499847Prof. Dr. med. Rainer BaderProf. Dr. med. Rainer Baderrosdok_disshab_0000001859-d1493164e107gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätThomas Josef DaubenProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlProf. Dr. med. Rainer BaderUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätThomas Josef DaubenProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlProf. Dr. med. Rainer BaderUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätThomas Josef DaubenRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00002037http://purl.uni-rostock.de/rosdok/id00002037urn:nbn:de:gbv:28-diss2018-0031-8biofilmosteoblastbacterial growthAn in vitro system for electrical stimulation of cells and bacteria was developed. Stimulation of cells and bacteria can be conducted under similar conditions. Prior to experiments, numerical simulations were performed. Methods for evaluation of effects were established. Stimulation showed significant effects on bacterial growth and biofilm mass production. Following stimulation, changes in extracellular DNA amounts were detected. In co-culture, stimulation led to increased CFU/ml S. epidermidis in supernatants, on and into MG63 cells on electrode surfaces and chamber bottom.20182018epub.dissertation1 Dissertation_Dauben_2018.pdf 2962514 8bc5d61663642d5fc54a3addc8dc4ae9 rosdok/id000020371016258844MODS updated during RosDok migration in June 2021DissertationHochschulschrift1154729249Thomas JosefDauben1989-VerfasserInautEstablishment of a novel in vitro implant infection modeleffects of electrical stimulation on staphylococci using alternating currenten114684618Prof. Dr. rer. nat.BerndKreikemeyerUniversitätsmedizin Rostock, Institut für Medizinische Mikrobiologie, Virologie und HygieneAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Institut für BiowissenschaftenAkademischeR BetreuerIndgs133499847Prof. Dr. med.RainerBaderUniversitätsmedizin Rostock, Orthopädische Klinik und Poliklinik, Forschungslabor für Biomechanik und ImplantattechnologieAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg10.18453/rosdok_id00002037http://purl.uni-rostock.de/rosdok/id00002037urn:nbn:de:gbv:28-diss2018-0031-8570 Biowissenschaften, BiologieMathematisch-Naturwissenschaftliche Fakultätfrei zugänglich (Open Access)Lizenz Metadaten: CC0Nutzungsrechte erteiltalle Rechte vorbehaltenUniversität RostockRostock2018monographic20182018Universitätsbibliothek RostockRostock20182018An in vitro system for electrical stimulation of cells and bacteria was developed. Stimulation of cells and bacteria can be conducted under similar conditions. Prior to experiments, numerical simulations were performed. Methods for evaluation of effects were established. Stimulation showed significant effects on bacterial growth and biofilm mass production. Following stimulation, changes in extracellular DNA amounts were detected. 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Bernd KreikemeyerProf. Dr. rer. nat. Bernd Kreikemeyerrosdok_disshab_0000001859-d1493164e76gnd:132475170Prof. Dr. rer. nat. Hubert BahlProf. Dr. rer. nat. Hubert Bahlrosdok_disshab_0000001859-d1493164e91gnd:133499847Prof. Dr. med. Rainer BaderProf. Dr. med. Rainer Baderrosdok_disshab_0000001859-d1493164e107gnd:2147083-2Universität Rostock Mathematisch-Naturwissenschaftliche FakultätUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätThomas Josef DaubenProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlProf. Dr. med. Rainer BaderUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätThomas Josef DaubenProf. Dr. rer. nat. Bernd KreikemeyerProf. Dr. rer. nat. Hubert BahlProf. Dr. med. Rainer BaderUniversität Rostock Mathematisch-Naturwissenschaftliche FakultätThomas Josef DaubenRostockUniversität Rostockepub.dissertation10.18453/rosdok_id00002037http://purl.uni-rostock.de/rosdok/id00002037urn:nbn:de:gbv:28-diss2018-0031-8biofilmosteoblastbacterial growthAn in vitro system for electrical stimulation of cells and bacteria was developed. Stimulation of cells and bacteria can be conducted under similar conditions. Prior to experiments, numerical simulations were performed. Methods for evaluation of effects were established. Stimulation showed significant effects on bacterial growth and biofilm mass production. Following stimulation, changes in extracellular DNA amounts were detected. In co-culture, stimulation led to increased CFU/ml S. epidermidis in supernatants, on and into MG63 cells on electrode surfaces and chamber bottom.20182018[xslt]Saxonrosdok/id00002037https://purl.uni-rostock.de/rosdok/id00002037101625884410.18453/rosdok_id00002037urn:nbn:de:gbv:28-diss2018-0031-8Thomas Josef DaubenDauben Thomas JosefEstablishment of a novel in vitro implant infection model : effects of electrical stimulation on staphylococci using alternating currentDissertationdoctoral thesisUniversität Rostock, 2018An in vitro system for electrical stimulation of cells and bacteria was developed. Stimulation of cells and bacteria can be conducted under similar conditions. Prior to experiments, numerical simulations were performed. Methods for evaluation of effects were established. Stimulation showed…Thomas Josef DaubenEstablishment of a novel in vitro implant infection modeleffects of electrical stimulation on staphylococci using alternating currentUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id000020371154729249Thomas JosefDauben1989-VerfasserInaut114684618Prof. Dr. rer. nat.BerndKreikemeyerUniversitätsmedizin Rostock, Institut für Medizinische Mikrobiologie, Virologie und HygieneAkademischeR BetreuerIndgs132475170Prof. Dr. rer. nat.HubertBahlUniversität Rostock, Institut für BiowissenschaftenAkademischeR BetreuerIndgs133499847Prof. Dr. med.RainerBaderUniversitätsmedizin Rostock, Orthopädische Klinik und Poliklinik, Forschungslabor für Biomechanik und ImplantattechnologieAkademischeR BetreuerIndgs2147083-2Universität RostockMathematisch-Naturwissenschaftliche FakultätGrad-verleihende Institutiondgg[doi]10.18453/rosdok_id00002037[purl]http://purl.uni-rostock.de/rosdok/id00002037[urn]urn:nbn:de:gbv:28-diss2018-0031-8open_access20182018epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:570institution:unirostock.mnfstate:published