10.18453/rosdok_id00002037 Dauben, Thomas Josef Thomas Josef Dauben http://d-nb.info/gnd/1154729249 Universität Rostock 2018 570 Life science 2018 en http://purl.uni-rostock.de/rosdok/id00002037 urn:nbn:de:gbv:28-diss2018-0031-8 An in vitro system for electrical stimulation of cells and bacteria was developed. Stimulation of cells and bacteria can be conducted under similar conditions. Prior to experiments, numerical simulations were performed. Methods for evaluation of effects were established. Stimulation showed significant effects on bacterial growth and biofilm mass production. Following stimulation, changes in extracellular DNA amounts were detected. In co-culture, stimulation led to increased CFU/ml S. epidermidis in supernatants, on and into MG63 cells on electrode surfaces and chamber bottom.