mycoreobjectrosdok_disshab_0000002274rosdok_disshab_0000002274rosdokdisshabrosdok_derivate_00000861722023-08-08T10:11:15.968Z2020-04-30T06:13:42.662ZadministratoreditorDpublished1rosdok_derivate_0000086172truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id000026611696923514Oau2020-04-302023-08-05T19:14:30ZrdaConverted from PICA to MODS using Pica2Mods XSLT Transformer 2.7 [SCM: "0c0e7a3c226a4a0cbcbec39b493c3c5257339ab8" "v2.7" "2023-08-04T00:00:00+0200"] with mode 'DEFAULT'.DissertationHochschulschriftMolecular recognition studies by nanoESI mass spectrometryAnalytical methods that characterize antibody-antigen interactions are certainly worth developing as they illuminate our understanding of molecular mechanisms of certain disease processes, and ultimately provide opportunities to improve existing treatment and management of such diseases by designing novel therapeutics. In this thesis, the challenges associated with the existing methods have been surpassed by developing simple but accurate nanoESI mass spectrometry methods which can be used to characterize antibody specificities as well as estimation of their binding affinities.Bright D.Danquah1987 -VerfasserInaut12092778590000-0002-6990-8434MichaelGlocker1960 -AkademischeR BetreuerIndgs10140521650000-0001-9190-482XChristopherGernerAkademischeR BetreuerIndgsGeorgFüllen1967 -AkademischeR BetreuerIndgs14062608538329-6Universität Rostock1419 -Grad-verleihende Institutiondgg1029510660Universitätsmedizin RostockGrad-verleihende Institutiondgghttp://purl.uni-rostock.de/rosdok/id00002661urn:nbn:de:gbv:28-rosdok_id00002661-610.18453/rosdok_id00002661500 Naturwissenschaften610 Medizin, GesundheitUniversitätsmedizinalle Rechte vorbehaltenNutzungsrechte erteiltLizenz Metadaten: CC0frei zugänglich (Open Access)en2019Universität RostockRostockmonographic201920192020Universitätsbibliothek RostockRostock2020Universitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00002661Enthält ZeitschriftenartikelMichael O. Glocker (Universität Rostock, Proteom Zentrum Rostock) ; Christopher Gerner (Universität Wien, Institut für Analytische Chemie) ; Georg Füllen (Universität Rostock, Institut für Biostatistik und Informatik in Medizin und Alternsforschung)vorgelegt von Bright Djan DanquahWX 2201Elektrospray-IonisationEpitopdoctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisSDNB:500SDNB:500500 Naturwissenschaften500 Natural sciencesSDNB:610SDNB:610610 Medizin, Gesundheit610 Medical sciences Medicineinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.umrinstitution:unirostock.umrUniversitätsmedizinUniversity MedicineUniversität Rostock. UniversitätsmedizinUniversitätsmedizinUni.Rostock.Fakultaet.MEDhttp://d-nb.info/gnd/1029510660licenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.rightsreservedlicenseinfo:work.rightsreservedalle Rechte vorbehaltenall rights reserved/creativecommons/r/reserved/0.9/88x31.png[DE-28]Urheberrechtsschutz 1.0$gRights Statements$uhttp://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/http://rightsstatements.org/vocab/InC/1.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2rfc5646:enrfc5646:enEnglischEnglishengengMolecular recognition studies by nanoESI mass spectrometryMolecular recognition studies by nanoESI mass spectrometrygnd:1209277859orcid:0000-0002-6990-8434gnd:1014052165orcid:0000-0001-9190-482Xgnd:140626085gnd:38329-6gnd:1029510660gnd:1209277859orcid:0000-0002-6990-8434gnd:1014052165orcid:0000-0001-9190-482Xgnd:140626085gnd:38329-6gnd:1029510660rosdok_disshab_0000002274-d3822778e52gnd:1209277859orcid:0000-0002-6990-8434Bright D. DanquahBright D. Danquahrosdok_disshab_0000002274-d3822778e68gnd:1014052165orcid:0000-0001-9190-482XMichael GlockerMichael Glockerrosdok_disshab_0000002274-d3822778e84Christopher GernerChristopher Gernerrosdok_disshab_0000002274-d3822778e94gnd:140626085Georg FüllenGeorg Füllenrosdok_disshab_0000002274-d3822778e109gnd:38329-6Universität RostockUniversität Rostockrosdok_disshab_0000002274-d3822778e120gnd:1029510660Universitätsmedizin RostockUniversitätsmedizin RostockBright D. DanquahMichael GlockerChristopher GernerGeorg FüllenUniversität RostockUniversitätsmedizin RostockBright D. DanquahMichael GlockerChristopher GernerGeorg FüllenUniversität RostockUniversitätsmedizin RostockBright D. DanquahRostockUniversität Rostockepub.dissertationhttp://purl.uni-rostock.de/rosdok/id00002661urn:nbn:de:gbv:28-rosdok_id00002661-610.18453/rosdok_id00002661WX 2201Elektrospray-IonisationEpitopAnalytical methods that characterize antibody-antigen interactions are certainly worth developing as they illuminate our understanding of molecular mechanisms of certain disease processes, and ultimately provide opportunities to improve existing treatment and management of such diseases by designing novel therapeutics. In this thesis, the challenges associated with the existing methods have been surpassed by developing simple but accurate nanoESI mass spectrometry methods which can be used to characterize antibody specificities as well as estimation of their binding affinities.20192019Enthält ZeitschriftenartikelMichael O. Glocker (Universität Rostock, Proteom Zentrum Rostock) ; Christopher Gerner (Universität Wien, Institut für Analytische Chemie) ; Georg Füllen (Universität Rostock, Institut für Biostatistik und Informatik in Medizin und Alternsforschung)vorgelegt von Bright Djan Danquahepub.dissertation1 Danquah_Dissertation_2020.pdf 7412933 f9cf7e64ef740579748592fa6e18c78d rosdok/id000026611696923514Oau2020-04-302023-08-05T19:14:30ZrdaConverted from PICA to MODS using Pica2Mods XSLT Transformer 2.7 [SCM: "0c0e7a3c226a4a0cbcbec39b493c3c5257339ab8" "v2.7" "2023-08-04T00:00:00+0200"] with mode 'DEFAULT'.DissertationHochschulschriftMolecular recognition studies by nanoESI mass spectrometryAnalytical methods that characterize antibody-antigen interactions are certainly worth developing as they illuminate our understanding of molecular mechanisms of certain disease processes, and ultimately provide opportunities to improve existing treatment and management of such diseases by designing novel therapeutics. In this thesis, the challenges associated with the existing methods have been surpassed by developing simple but accurate nanoESI mass spectrometry methods which can be used to characterize antibody specificities as well as estimation of their binding affinities.Bright D.Danquah1987 -VerfasserInaut12092778590000-0002-6990-8434MichaelGlocker1960 -AkademischeR BetreuerIndgs10140521650000-0001-9190-482XChristopherGernerAkademischeR BetreuerIndgsGeorgFüllen1967 -AkademischeR BetreuerIndgs14062608538329-6Universität Rostock1419 -Grad-verleihende Institutiondgg1029510660Universitätsmedizin RostockGrad-verleihende Institutiondgghttp://purl.uni-rostock.de/rosdok/id00002661urn:nbn:de:gbv:28-rosdok_id00002661-610.18453/rosdok_id00002661500 Naturwissenschaften610 Medizin, GesundheitUniversitätsmedizinalle Rechte vorbehaltenNutzungsrechte erteiltLizenz Metadaten: CC0frei zugänglich (Open Access)en2019Universität RostockRostockmonographic201920192020Universitätsbibliothek RostockRostock2020Universitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00002661Enthält ZeitschriftenartikelMichael O. Glocker (Universität Rostock, Proteom Zentrum Rostock) ; Christopher Gerner (Universität Wien, Institut für Analytische Chemie) ; Georg Füllen (Universität Rostock, Institut für Biostatistik und Informatik in Medizin und Alternsforschung)vorgelegt von Bright Djan DanquahWX 2201Elektrospray-IonisationEpitop 2020-04-30T06:13:42.662Z 2023-08-08T10:11:15.968Z 2023-08-18T10:11:15.973Z {"identifier":"rosdok/id00002661","type":"local_id","additional":"","service":"MCRLocalID","created":"2020-04-30T06:13:43.227Z"} editorD {"identifier":"http://purl.uni-rostock.de/rosdok/id00002661","type":"purl","additional":"","service":"RosDokPURL","created":"2020-04-30T06:23:17.591Z","registered":"2020-04-30T06:23:17.591Z"} {"identifier":"10.18453/rosdok_id00002661","type":"doi","additional":"","service":"RosDokDOI","created":"2020-04-30T06:23:21.507Z","registered":"2020-04-30T06:23:21.507Z"} {"identifier":"urn:nbn:de:gbv:28-rosdok_id00002661-6","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2020-04-30T06:13:43.692Z","registered":"2020-05-01T02:01:21.497Z"} administratorfulltextfile/rosdok_disshab_0000002274/rosdok_derivate_0000086172/Danquah_Dissertation_2020.pdfMolecular recognition studies by nanoESI mass spectrometryMolecular recognition studies by nanoESI mass spectrometrygnd:1209277859orcid:0000-0002-6990-8434gnd:1014052165orcid:0000-0001-9190-482Xgnd:140626085gnd:38329-6gnd:1029510660gnd:1209277859orcid:0000-0002-6990-8434gnd:1014052165orcid:0000-0001-9190-482Xgnd:140626085gnd:38329-6gnd:1029510660rosdok_disshab_0000002274-d3822778e52gnd:1209277859orcid:0000-0002-6990-8434Bright D. DanquahBright D. Danquahrosdok_disshab_0000002274-d3822778e68gnd:1014052165orcid:0000-0001-9190-482XMichael GlockerMichael Glockerrosdok_disshab_0000002274-d3822778e84Christopher GernerChristopher Gernerrosdok_disshab_0000002274-d3822778e94gnd:140626085Georg FüllenGeorg Füllenrosdok_disshab_0000002274-d3822778e109gnd:38329-6Universität RostockUniversität Rostockrosdok_disshab_0000002274-d3822778e120gnd:1029510660Universitätsmedizin RostockUniversitätsmedizin RostockBright D. DanquahMichael GlockerChristopher GernerGeorg FüllenUniversität RostockUniversitätsmedizin RostockBright D. DanquahMichael GlockerChristopher GernerGeorg FüllenUniversität RostockUniversitätsmedizin RostockBright D. DanquahRostockUniversität Rostockepub.dissertationhttp://purl.uni-rostock.de/rosdok/id00002661urn:nbn:de:gbv:28-rosdok_id00002661-610.18453/rosdok_id00002661WX 2201Elektrospray-IonisationEpitopAnalytical methods that characterize antibody-antigen interactions are certainly worth developing as they illuminate our understanding of molecular mechanisms of certain disease processes, and ultimately provide opportunities to improve existing treatment and management of such diseases by designing novel therapeutics. In this thesis, the challenges associated with the existing methods have been surpassed by developing simple but accurate nanoESI mass spectrometry methods which can be used to characterize antibody specificities as well as estimation of their binding affinities.20192019Enthält ZeitschriftenartikelMichael O. Glocker (Universität Rostock, Proteom Zentrum Rostock) ; Christopher Gerner (Universität Wien, Institut für Analytische Chemie) ; Georg Füllen (Universität Rostock, Institut für Biostatistik und Informatik in Medizin und Alternsforschung)vorgelegt von Bright Djan Danquah[xslt]Saxonrosdok/id00002661https://purl.uni-rostock.de/rosdok/id00002661169692351410.18453/rosdok_id00002661urn:nbn:de:gbv:28-rosdok_id00002661-6Bright D. DanquahDanquah Bright D.Molecular recognition studies by nanoESI mass spectrometryDissertationdoctoral thesisUniversität Rostock, 2019Analytical methods that characterize antibody-antigen interactions are certainly worth developing as they illuminate our understanding of molecular mechanisms of certain disease processes, and ultimately provide opportunities to improve existing treatment and management of such diseases by designing…Bright D. DanquahMolecular recognition studies by nanoESI mass spectrometryUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00002661Bright D.Danquah1987 -VerfasserInaut12092778590000-0002-6990-8434MichaelGlocker1960 -AkademischeR BetreuerIndgs10140521650000-0001-9190-482XChristopherGernerAkademischeR BetreuerIndgsGeorgFüllen1967 -AkademischeR BetreuerIndgs14062608538329-6Universität Rostock1419 -Grad-verleihende Institutiondgg1029510660Universitätsmedizin RostockGrad-verleihende Institutiondgg[purl]http://purl.uni-rostock.de/rosdok/id00002661[urn]urn:nbn:de:gbv:28-rosdok_id00002661-6[doi]10.18453/rosdok_id00002661open_access20192019epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:500SDNB:610institution:unirostock.umrstate:published