10.18453/rosdok_id00002925 Schröder, Annemarie Annemarie Schröder http://d-nb.info/gnd/1227070551 https://orcid.org/0000-0002-5452-2731 Universität Rostock 2020 570 Life science 610 Medical sciences Medicine 2020 de http://purl.uni-rostock.de/rosdok/id00002925 urn:nbn:de:gbv:28-rosdok_id00002925-6 Within breast tissue, adipose-derived stem cells (ADSCs) are responsible for maintaining cellular homeostasis. However, this potential can also contributed to the undesirable effect of tumor promotion. Therefore, this work deals with the effect of ionizing radiation on these interactions. In summary, the promoting effects of ADSCs on MCF-7 breast cancer cells were neutralized or reversed by a radiation treatment. Furthermore, ADSCs exhibit a medium radiation sensitivity associated with a functional DNA repair system.