10.18453/rosdok_id00004037 Frey, Anna Katharina Anna Katharina Frey http://d-nb.info/gnd/1274137349 Universität Rostock 2022 500 Natural sciences 540 Chemistry & allied sciences 2022 en http://purl.uni-rostock.de/rosdok/id00004037 urn:nbn:de:gbv:28-rosdok_id00004037-0 This dissertation deals with the synthesis of small molecules for use in skin cancers with possible plasma application. First, N-glycosylated oxindoles and N-glycosylated isatins bearing electron-withdrawing substituents were synthesized. Furthermore, highly functionalized synthetic building blocks were synthesized in regio- and chemo selective palladium-catalyzed coupling reactions with various boronic acids and alkynes, which then reacted to form heterocycles by acid-mediated cycloisomerization or alkyne-carbonyl metathesis.