10.18453/rosdok_id00004044 Kamaleddine, Imad Imad Kamaleddine http://d-nb.info/gnd/1247129918 Universität Rostock 2021 610 Medical sciences Medicine 2021 de http://purl.uni-rostock.de/rosdok/id00004044 urn:nbn:de:gbv:28-rosdok_id00004044-7 Transsphincteric Anal fistula remains a challenging issue for both surgeons & patients. Aggressive treatments are associated with high risk of incontinence whereas minimally invasive methods might lead to more recurrences. 4 Pigs (Sus Scrofa Domesticus) underwent a surgical creation of 4 iatrogenic transsphincteric anal fistulas by each animal in the supine positions 2, 5, 8 and 11 o’clock. 6/12 Fistulas were treated by Vacuum therapy. All treated fistulas healed very well and showed no adverse reactions. This new therapy is feasible and safe.