10.18453/rosdok_id00004295 Bourriquen, Florian Marwan Florian Marwan Bourriquen http://d-nb.info/gnd/1289642907 https://orcid.org/0000-0002-3895-7321 Universität Rostock 2022 540 Chemistry & allied sciences 2022 en http://purl.uni-rostock.de/rosdok/id00004295 urn:nbn:de:gbv:28-rosdok_id00004295-8 This dissertation reports the development of new catalytic methodologies for deuterium incorporation into organic molecules. In a first part, the use of a simple Lewis acid is reported for the isotopic labelling of electron-rich (hetero)arenes. Next, two heterogeneous catalysts are presented for the labelling of comparable compounds: a first-generation iron-based system and a follow-up work using manganese. Both materials are easily prepared and fully characterised. Additionally, investigations were performed to gain insight on the mechanisms.