mycoreobjectrosdok_disshab_0000002992rosdok_disshab_0000002992rosdokdisshabrosdok_derivate_00002088182023-08-08T10:15:37.581Z2023-07-05T11:01:28.097ZadministratoreditorMSpublished1rosdok_derivate_0000208818truetruederivate_types:fulltextVolltextfulltextwf_edit_epub wf_register_epubstate:publishedstate:publishedveröffentlichtpublishedrosdok/id000043441851811249Oau2023-07-052023-08-05T19:23:09ZrdaConverted from PICA to MODS using Pica2Mods XSLT Transformer 2.7 [SCM: "0c0e7a3c226a4a0cbcbec39b493c3c5257339ab8" "v2.7" "2023-08-04T00:00:00+0200"] with mode 'DEFAULT'.DissertationHochschulschriftDistress analysis of mice used for translational researchreflection of a surgeon on animal welfareThe assessment and improvement of animal welfare is not only an ethical requirement, but also a guarantee of efficient and high quality translational research. In recent years, sophisticated animal models were created to study human diseases. However, the assessment of distress in these animal models is scarce. In order to provide a solid basis for optimizing animal welfare in future studies, body weight, burrowing, nesting activity, faecal corticosterone metabolites (FCMs), and distress scores were analyzed in several animal models.WentaoXie1984 -VerfasserInaut1294481479DietmarZechner1969 -AkademischeR BetreuerIndgs11038361450000-0002-2075-7540Universitätsmedizin RostockHugo IstvanMurua Escobar1973 -AkademischeR BetreuerIndgs12980455XUteLindauerAkademischeR BetreuerIndgs112429270RWTH Aachen38329-6Universität Rostock1419 -Grad-verleihende Institutiondgg1029510660Universitätsmedizin RostockGrad-verleihende Institutiondgghttp://purl.uni-rostock.de/rosdok/id00004344urn:nbn:de:gbv:28-rosdok_id00004344-610.18453/rosdok_id00004344570 Biowissenschaften, Biologie610 Medizin, GesundheitUniversitätsmedizinCC BY 4.0Nutzungsrechte erteiltLizenz Metadaten: CC0frei zugänglich (Open Access)en2022Universität RostockRostockmonographic202320222023Universitätsbibliothek RostockRostock2023Universitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00004344Enthält ZeitschriftenartikelPublications: Wentao Xie, Marcel Kordt, Rupert Palme, Eberhard Grambow, Brigitte Vollmar, Dietmar Zechner. Diagnostic Ability of Methods Depicting Distress of Tumor-Bearing Mice. Animals. 2021;1:2155. Wentao Xie, Rupert Palme, Clemens Schafmayer, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow. Distress Analysis of Mice with Cervical Arteriovenous Fistulas. Animals. 2021;11:3051. WentaoXie, Matthias Lorenz, Friederike Poosch, Rupert Palme, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow, Daniel Strüder. 3D-printed lightweight dorsal skin fold chambers from PEEK reduce chamber-related animal distress. Sci Rep. 2022;12:11599.Dietmar Zechner (Universitätsmedizin Rostock) ; Hugo Murua Escobar (Universitätsmedizin Rostock) ; Ute Lindauer (RWTH Aachen)[{"name":"Zechner, Dietmar","affil":"Universitätsmedizin Rostock"},{"name":"Murua Escobar, Hugo","affil":"Universitätsmedizin Rostock"},{"name":"Lindauer, Ute","affil":"RWTH Aachen"}]vorgelegt von Wentao XieZechner, DietmarUniversitätsmedizin RostockMurua Escobar, HugoUniversitätsmedizin RostockLindauer, UteRWTH Aachendoctype:epubdoctype:epubDokumenttypDocument typedoctype:epub.dissertationdoctype:epub.dissertationDissertationdoctoral thesisdiniPublType:doctoralThesis diniPublType2022:PhDThesis XMetaDissPlusThesisLevel:thesis.doctoralinfo:eu-repo/semantics/doctoralThesisdocumentnatureOfContent:ppn_105825778natureOfContent:ppn_105825778HochschulschriftdiniPublType2022:DoctoralThesisdiniPublType2022:DoctoralThesisDissertation oder HabilitationDoctoral thesisDRIVERdiniPublType2022:PhDThesisdiniPublType2022:PhDThesisDissertationPhD thesisKDSF (Pu34)XMetaDissPlusThesisLevel:thesis.doctoralXMetaDissPlusThesisLevel:thesis.doctoralDoktorarbeitdoctoral thesisSDNB:570SDNB:570570 Biowissenschaften, Biologie570 Life scienceSDNB:610SDNB:610610 Medizin, Gesundheit610 Medical sciences Medicineinstitution:unirostockinstitution:unirostockUniversität RostockUniversity of RostockUniversität RostockUniversität RostockUni.Rostockhttp://d-nb.info/gnd/38329-6institution:unirostock.umrinstitution:unirostock.umrUniversitätsmedizinUniversity MedicineUniversität Rostock. UniversitätsmedizinUniversitätsmedizinUni.Rostock.Fakultaet.MEDhttp://d-nb.info/gnd/1029510660licenseinfo:worklicenseinfo:workWerkworklicenseinfo:work.cclicenselicenseinfo:work.cclicenseCC-LizenzCC-licenselicenseinfo:work.cclicense.cc-bylicenseinfo:work.cclicense.cc-byCC BYCC BYlicenseinfo:work.cclicense.cc-by.v40licenseinfo:work.cclicense.cc-by.v40CC BY 4.0CC BY 4.0/creativecommons/l/by/4.0/88x31.png[DE-28]Namensnennung 4.0 International$cCC BY 4.0$gCreative Commons$uhttps://creativecommons.org/licenses/by/4.0/https://creativecommons.org/licenses/by/4.0/https://creativecommons.org/licenses/by/4.0/licenseinfo:depositlicenseinfo:depositVeröffentlichungsgenehmigungpermission to storelicenseinfo:deposit.rightsgrantedlicenseinfo:deposit.rightsgrantedNutzungsrechte erteiltrights grantedlicenseinfo:metadatalicenseinfo:metadataLizenzen für Metadatenlicenseinfo:metadata.cc0licenseinfo:metadata.cc0Lizenz Metadaten: CC0license metadata: CC0/creativecommons/p/zero/1.0/88x31.pnghttps://creativecommons.org/publicdomain/zero/1.0/accesscondition:openaccessaccesscondition:openaccessfrei zugänglich (Open Access)open accesshttp://purl.org/coar/access_right/c_abf2OAfreeinfo:eu-repo/semantics/openAccess[DE-28]Open Access$gControlled Vocabulary for Access Rights$uhttp://purl.org/coar/access_right/c_abf2rfc5646:enrfc5646:enEnglischEnglishengengDistress analysis of mice used for translational researchreflection of a surgeon on animal welfareDistress analysis of mice used for translational researchreflection of a surgeon on animal welfaregnd:1294481479gnd:1103836145orcid:0000-0002-2075-7540gnd:12980455Xgnd:112429270gnd:38329-6gnd:1029510660gnd:1294481479gnd:1103836145orcid:0000-0002-2075-7540gnd:12980455Xgnd:112429270gnd:38329-6gnd:1029510660rosdok_disshab_0000002992-d2224282e53gnd:1294481479Wentao XieWentao Xierosdok_disshab_0000002992-d2224282e67gnd:1103836145orcid:0000-0002-2075-7540Dietmar ZechnerDietmar Zechnerrosdok_disshab_0000002992-d2224282e84gnd:12980455XHugo Istvan Murua EscobarHugo Istvan Murua Escobarrosdok_disshab_0000002992-d2224282e98gnd:112429270Ute LindauerUte Lindauerrosdok_disshab_0000002992-d2224282e112gnd:38329-6Universität RostockUniversität Rostockrosdok_disshab_0000002992-d2224282e123gnd:1029510660Universitätsmedizin RostockUniversitätsmedizin RostockWentao XieDietmar ZechnerHugo Istvan Murua EscobarUte LindauerUniversität RostockUniversitätsmedizin RostockWentao XieDietmar ZechnerHugo Istvan Murua EscobarUte LindauerUniversität RostockUniversitätsmedizin RostockWentao XieRostockUniversität Rostockepub.dissertationhttp://purl.uni-rostock.de/rosdok/id00004344urn:nbn:de:gbv:28-rosdok_id00004344-610.18453/rosdok_id00004344The assessment and improvement of animal welfare is not only an ethical requirement, but also a guarantee of efficient and high quality translational research. In recent years, sophisticated animal models were created to study human diseases. However, the assessment of distress in these animal models is scarce. In order to provide a solid basis for optimizing animal welfare in future studies, body weight, burrowing, nesting activity, faecal corticosterone metabolites (FCMs), and distress scores were analyzed in several animal models.20222022Enthält ZeitschriftenartikelPublications: Wentao Xie, Marcel Kordt, Rupert Palme, Eberhard Grambow, Brigitte Vollmar, Dietmar Zechner. Diagnostic Ability of Methods Depicting Distress of Tumor-Bearing Mice. Animals. 2021;1:2155. Wentao Xie, Rupert Palme, Clemens Schafmayer, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow. Distress Analysis of Mice with Cervical Arteriovenous Fistulas. Animals. 2021;11:3051. WentaoXie, Matthias Lorenz, Friederike Poosch, Rupert Palme, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow, Daniel Strüder. 3D-printed lightweight dorsal skin fold chambers from PEEK reduce chamber-related animal distress. Sci Rep. 2022;12:11599.Dietmar Zechner (Universitätsmedizin Rostock) ; Hugo Murua Escobar (Universitätsmedizin Rostock) ; Ute Lindauer (RWTH Aachen)[{"name":"Zechner, Dietmar","affil":"Universitätsmedizin Rostock"},{"name":"Murua Escobar, Hugo","affil":"Universitätsmedizin Rostock"},{"name":"Lindauer, Ute","affil":"RWTH Aachen"}]vorgelegt von Wentao Xieepub.dissertation1 Xie_Dissertation_2023.pdf 4490587 4488da65048d976a4901db336142baa0 rosdok/id000043441851811249Oau2023-07-052023-08-05T19:23:09ZrdaConverted from PICA to MODS using Pica2Mods XSLT Transformer 2.7 [SCM: "0c0e7a3c226a4a0cbcbec39b493c3c5257339ab8" "v2.7" "2023-08-04T00:00:00+0200"] with mode 'DEFAULT'.DissertationHochschulschriftDistress analysis of mice used for translational researchreflection of a surgeon on animal welfareThe assessment and improvement of animal welfare is not only an ethical requirement, but also a guarantee of efficient and high quality translational research. In recent years, sophisticated animal models were created to study human diseases. However, the assessment of distress in these animal models is scarce. In order to provide a solid basis for optimizing animal welfare in future studies, body weight, burrowing, nesting activity, faecal corticosterone metabolites (FCMs), and distress scores were analyzed in several animal models.WentaoXie1984 -VerfasserInaut1294481479DietmarZechner1969 -AkademischeR BetreuerIndgs11038361450000-0002-2075-7540Universitätsmedizin RostockHugo IstvanMurua Escobar1973 -AkademischeR BetreuerIndgs12980455XUteLindauerAkademischeR BetreuerIndgs112429270RWTH Aachen38329-6Universität Rostock1419 -Grad-verleihende Institutiondgg1029510660Universitätsmedizin RostockGrad-verleihende Institutiondgghttp://purl.uni-rostock.de/rosdok/id00004344urn:nbn:de:gbv:28-rosdok_id00004344-610.18453/rosdok_id00004344570 Biowissenschaften, Biologie610 Medizin, GesundheitUniversitätsmedizinCC BY 4.0Nutzungsrechte erteiltLizenz Metadaten: CC0frei zugänglich (Open Access)en2022Universität RostockRostockmonographic202320222023Universitätsbibliothek RostockRostock2023Universitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00004344Enthält ZeitschriftenartikelPublications: Wentao Xie, Marcel Kordt, Rupert Palme, Eberhard Grambow, Brigitte Vollmar, Dietmar Zechner. Diagnostic Ability of Methods Depicting Distress of Tumor-Bearing Mice. Animals. 2021;1:2155. Wentao Xie, Rupert Palme, Clemens Schafmayer, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow. Distress Analysis of Mice with Cervical Arteriovenous Fistulas. Animals. 2021;11:3051. WentaoXie, Matthias Lorenz, Friederike Poosch, Rupert Palme, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow, Daniel Strüder. 3D-printed lightweight dorsal skin fold chambers from PEEK reduce chamber-related animal distress. Sci Rep. 2022;12:11599.Dietmar Zechner (Universitätsmedizin Rostock) ; Hugo Murua Escobar (Universitätsmedizin Rostock) ; Ute Lindauer (RWTH Aachen)[{"name":"Zechner, Dietmar","affil":"Universitätsmedizin Rostock"},{"name":"Murua Escobar, Hugo","affil":"Universitätsmedizin Rostock"},{"name":"Lindauer, Ute","affil":"RWTH Aachen"}]vorgelegt von Wentao Xie Zechner, Dietmar Universitätsmedizin Rostock Murua Escobar, Hugo Universitätsmedizin Rostock Lindauer, Ute RWTH Aachen 2023-07-05T11:01:28.097Z 2023-08-08T10:15:37.581Z 2023-08-18T10:15:37.586Z {"identifier":"rosdok/id00004344","type":"local_id","additional":"","service":"MCRLocalID","created":"2023-07-05T11:01:28.116Z","registered":"2023-07-05T11:01:28.116Z"} editorMS {"identifier":"urn:nbn:de:gbv:28-rosdok_id00004344-6","type":"dnbUrn","additional":"","service":"RosDokURN","created":"2023-07-05T11:01:28.121Z","registered":"2023-07-06T06:46:40.460Z"} administratorfulltextfile/rosdok_disshab_0000002992/rosdok_derivate_0000208818/Xie_Dissertation_2023.pdfDistress analysis of mice used for translational researchreflection of a surgeon on animal welfareDistress analysis of mice used for translational researchreflection of a surgeon on animal welfaregnd:1294481479gnd:1103836145orcid:0000-0002-2075-7540gnd:12980455Xgnd:112429270gnd:38329-6gnd:1029510660gnd:1294481479gnd:1103836145orcid:0000-0002-2075-7540gnd:12980455Xgnd:112429270gnd:38329-6gnd:1029510660rosdok_disshab_0000002992-d2224282e53gnd:1294481479Wentao XieWentao Xierosdok_disshab_0000002992-d2224282e67gnd:1103836145orcid:0000-0002-2075-7540Dietmar ZechnerDietmar Zechnerrosdok_disshab_0000002992-d2224282e84gnd:12980455XHugo Istvan Murua EscobarHugo Istvan Murua Escobarrosdok_disshab_0000002992-d2224282e98gnd:112429270Ute LindauerUte Lindauerrosdok_disshab_0000002992-d2224282e112gnd:38329-6Universität RostockUniversität Rostockrosdok_disshab_0000002992-d2224282e123gnd:1029510660Universitätsmedizin RostockUniversitätsmedizin RostockWentao XieDietmar ZechnerHugo Istvan Murua EscobarUte LindauerUniversität RostockUniversitätsmedizin RostockWentao XieDietmar ZechnerHugo Istvan Murua EscobarUte LindauerUniversität RostockUniversitätsmedizin RostockWentao XieRostockUniversität Rostockepub.dissertationhttp://purl.uni-rostock.de/rosdok/id00004344urn:nbn:de:gbv:28-rosdok_id00004344-610.18453/rosdok_id00004344The assessment and improvement of animal welfare is not only an ethical requirement, but also a guarantee of efficient and high quality translational research. In recent years, sophisticated animal models were created to study human diseases. However, the assessment of distress in these animal models is scarce. In order to provide a solid basis for optimizing animal welfare in future studies, body weight, burrowing, nesting activity, faecal corticosterone metabolites (FCMs), and distress scores were analyzed in several animal models.20222022Enthält ZeitschriftenartikelPublications: Wentao Xie, Marcel Kordt, Rupert Palme, Eberhard Grambow, Brigitte Vollmar, Dietmar Zechner. Diagnostic Ability of Methods Depicting Distress of Tumor-Bearing Mice. Animals. 2021;1:2155. Wentao Xie, Rupert Palme, Clemens Schafmayer, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow. Distress Analysis of Mice with Cervical Arteriovenous Fistulas. Animals. 2021;11:3051. WentaoXie, Matthias Lorenz, Friederike Poosch, Rupert Palme, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow, Daniel Strüder. 3D-printed lightweight dorsal skin fold chambers from PEEK reduce chamber-related animal distress. Sci Rep. 2022;12:11599.Dietmar Zechner (Universitätsmedizin Rostock) ; Hugo Murua Escobar (Universitätsmedizin Rostock) ; Ute Lindauer (RWTH Aachen)[{"name":"Zechner, Dietmar","affil":"Universitätsmedizin Rostock"},{"name":"Murua Escobar, Hugo","affil":"Universitätsmedizin Rostock"},{"name":"Lindauer, Ute","affil":"RWTH Aachen"}]vorgelegt von Wentao Xie[xslt]Saxonrosdok/id00004344https://purl.uni-rostock.de/rosdok/id00004344185181124910.18453/rosdok_id00004344urn:nbn:de:gbv:28-rosdok_id00004344-6Wentao XieXie WentaoDistress analysis of mice used for translational research : reflection of a surgeon on animal welfareDissertationdoctoral thesisUniversität Rostock, 2022The assessment and improvement of animal welfare is not only an ethical requirement, but also a guarantee of efficient and high quality translational research. In recent years, sophisticated animal models were created to study human diseases. However, the assessment of distress in these animal…Wentao XieDistress analysis of mice used for translational researchreflection of a surgeon on animal welfareUniversitätsbibliothek Rostockhttp://purl.uni-rostock.de/rosdok/id00004344WentaoXie1984 -VerfasserInaut1294481479DietmarZechner1969 -AkademischeR BetreuerIndgs11038361450000-0002-2075-7540Universitätsmedizin RostockHugo IstvanMurua Escobar1973 -AkademischeR BetreuerIndgs12980455XUteLindauerAkademischeR BetreuerIndgs112429270RWTH Aachen38329-6Universität Rostock1419 -Grad-verleihende Institutiondgg1029510660Universitätsmedizin RostockGrad-verleihende Institutiondgg[purl]http://purl.uni-rostock.de/rosdok/id00004344[urn]urn:nbn:de:gbv:28-rosdok_id00004344-6[doi]10.18453/rosdok_id00004344open_access20222022epoch:21th_centuryrfc5646:endoctype:epub.dissertationaccesscondition:openaccessSDNB:570SDNB:610institution:unirostock.umrstate:published