Incidentially discovered adrenal non-producing adenomas do show signs of glucocorticoid excess

10.18453/rosdok_id00004402 Winzinger, Eliza-Paula Eliza-Paula Winzinger http://d-nb.info/gnd/1298853117 Incidentially discovered adrenal non-producing adenomas do show signs of glucocorticoid excess Universität Rostock 2022 610 Medical sciences Medicine 2022 en http://purl.uni-rostock.de/rosdok/id00004402 urn:nbn:de:gbv:28-rosdok_id00004402-3 We asked whether subtle laboratory abnormalities in parameters that reflect glucocorticoid action can be found in patients with non-producing adrenocortical adenomas (NPA). We found that patients with adrenal non-producing adenomas already showed signs of glucocorticoid excess, including relative lymphocytopenia, lowered DHEAS and ACTH concentrations. We also found that the extent of lymphocytopenia correlated well with the concentrations of DHEAS and ACTH, and DHEAS correlated well with ACTH concentrations.