10.18453/rosdok_id00004620 Mohebali, Nooshin Nooshin Mohebali http://d-nb.info/gnd/1334329893 Universität Rostock 2023 500 Natural sciences 2023 en https://purl.uni-rostock.de/rosdok/id00004620 urn:nbn:de:gbv:28-rosdok_id00004620-5 This study investigates the role of three commensal bacteria - Faecalibacterium prausnitzii, Bacteroides faecis, and Roseburia intestinalis - in maintaining intestinal barrier integrity and their potential to mitigate chronic inflammation, with a focus on Ulcerative Colitis (UC). Using in vitro and in vivo models, the study demonstrates that these bacteria alleviate inflammatory-induced impairment of the intestinal barrier, enhance barrier function, and mitigate pro-inflammatory processes.