10.18453/rosdok_id00004672 Ghasemian, Khadijeh Khadijeh Ghasemian http://d-nb.info/gnd/1341425274 Universität Rostock 2023 580 Botanical sciences 630 Agriculture 2023 en https://purl.uni-rostock.de/rosdok/id00004672 urn:nbn:de:gbv:28-rosdok_id00004672-2 The aim of the study was to develop strategies to produce an oral contraceptive vaccine for mice in plants, in order to reduce the mouse population. The results showed that mouse-specific contraceptive peptides were successfully produced in plants. All peptides induced IgG antibodies in subcutaneously vaccinated mice. Moreover, oral delivery of the leaves expressing a fusion protein elicited systemic and mucosal cross-reactive antibodies. Observations suggest that plant-produced contraceptives have the potential to be used in the development of feeding baits to reduce the fertility of mice.