10.18453/rosdok_id00004888 Sobhani, Maryam Maryam Sobhani http://d-nb.info/gnd/1372671455 Universität Rostock 2024 540 Chemistry & allied sciences 2024 en https://purl.uni-rostock.de/rosdok/id00004888 urn:nbn:de:gbv:28-rosdok_id00004888-1 The aim of this dissertation is to develop an efficient methodology for the design of several new carbo- and heterocycles. The focus is on using Alkyne-Carbonyl Metathesis (ACM) reaction due to its high atom economy and efficiency. In this regard, a metal free, Brønsted acid mediated intramolecular ACM reaction has been developed to form new seven- and six-membered carbocycles. In general, regio- and chemoselective palladium-catalyzed cross-coupling reactions with various boronic acids and alkynes were applied in all studies to synthesize the precursors for the ring closing ACM reaction.