10.18453/rosdok_id00005086 Welzen, Matti Matti Welzen http://d-nb.info/gnd/1388339641 https://orcid.org/0000-0002-2486-0246 Universität Rostock 2024 004 Data processing Computer sciences 610 Medical sciences Medicine 2024 en https://purl.uni-rostock.de/rosdok/id00005086 urn:nbn:de:gbv:28-rosdok_id00005086-2 The interpretation of biomolecular data is often challenging due to the heterogeneity in the structural and functional organization of biological systems. In this thesis, I created knowledge graphs of disease processes, published as interactive Disease Maps, and developed new tools for their analysis. I present (i) the Atlas of Inflammation Resolution (AIR), (ii) the two-dimensional enrichment analysis (2DEA) as a novel network-based enrichment approach, (iii) the Sarcopenia Map linking gastrointestinal diseases and sarcopenia, and (iv) the MASLD Map investigating steatotic liver diseases.