10.18453/rosdok_id00005135 Dam, Phong Phong Dam http://d-nb.info/gnd/1360483020 https://orcid.org/0000-0003-3438-181X Universität Rostock 2024 540 Chemistry & allied sciences 2024 en https://purl.uni-rostock.de/rosdok/id00005135 urn:nbn:de:gbv:28-rosdok_id00005135-9 This dissertation investigates the broad potential of cobalt catalysis in open-shell transformations, positioning cobalt as a sustainable, versatile alternative to noble metals for conducting complex organic reactions under mild conditions. The thesis is organized into four projects, each contributing unique insights into cobalt's role in radical desaturation and selective functionalization of various organic molecules. The combination of both experimental and theoretical approach delivered a comprehensive understanding of cobalt’s reactivity and selectivity.