10.18453/rosdok_id00005205 Song, Zezhong Zezhong Song http://d-nb.info/gnd/1393423531 Universität Rostock 2024 570 Life science 610 Medical sciences Medicine 2024 en https://purl.uni-rostock.de/rosdok/id00005205 urn:nbn:de:gbv:28-rosdok_id00005205-6 In cell-based therapy for cartilage repair, preventing fibrocartilage formation due to dedifferentiation is crucial. This study examined how alternating electric fields affect the redifferentiation of human chondrocytes from male and female donors. Stimulation at 15–20 V/m increased the Col2/Col1 ratio and promoted rounded morphology, indicating enhanced redifferentiation. Meanwhile, female chondrocytes showed more collagen 1 production and fibroblast-like shape. These results suggest male chondrocytes showed higher tendency towards redifferentiation in response to electrical stimulation.