Universität Rostock, 2008
Abstract: In the present work the synthesis of D-galacturonic acid N- and C-glycosides is described. Several protecting strategies were investigated for the synthesis and structural characterization of 1-azido and C-allyl galacturonates as suitable building blocks. Derivatization of azido and C-allyl moieties is described resulting in biotinylated compounds which can be used for the synthesis of labelled pectin fragments. Such biotinylated fragments are useful tools in biochemical assays.
doctoral thesis free access