Universität Rostock, 2007
Abstract: Transcription analysis showed that temporary feeding of a soy protein isolate (characterized by an imbalanced amino acid pattern) to growing pigs resulted in prolonged up-regulation of genes involved in oxidative stress response as compared to the Casein- diet (balanced amino acid composition). The SPI-diet associated with prolonged oxidative stress response was identified as a molecular mechanism of the persistent growth retardation in juvenile pigs. DNA methylation is a possible mechanism for the diet associated persistent alterations of hepatic expressions of genes involved in oxidative stress response.
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