Universität Rostock, 2008
Abstract: Before a new cochlear implant electrode becomes clinical practice an ex vivo implantation study has to assess the effects of theses electrodes on the post implantation integrity of the cochlear membrane structures. A definite determination between membranous trauma caused by preparative method or electrode insertion has to be warranted. We conducted a novel conservative ex vivo freeze grinding technique for native temporal bones. Optimal parameters for histology, immunohistochemistry and documentation have been established.
doctoral thesis free access