| title: |
| Identification and analysis of functional candidate genes for the inverted teat defect
in pigs |
|
| contributing persons: |
| Sylvio Tetzlaff[VerfasserIn] |
 |
139069127 |
| Reinhard Schröder
, Prof. Dr.[AkademischeR BetreuerIn] |
| Klaus Wimmers
, Prof. Dr.[AkademischeR BetreuerIn] |
| Karl Schellander
, Prof. Dr.[AkademischeR BetreuerIn] |
|
| contributing corporate bodies: |
| Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
|
2147083-2 |
|
| |
| abstract: |
|
PTHR1 and LEF1 were analyzed as functional candidate genes for the inverted teat defect
in pigs. SNP in both genes could be shown as significantly associated with inverted
teats. QTL analyses revealed significant QTL on twelve chromosomes in an experimental
and five chromosomes in a commercial pig population. That enabled the information
about novel positional candidate genes. Adjacent microarray analyses of epithelial
and mesenchymal teat tissues of affected and non-affected animals offered differentially
regulated genes. Constitutive quantitative real-time analyses of FGFR2, GHR, HGF,
PDGFA, PDGFRA, PDGFB and VEGF revealed significant differential expressions in the
compared tissues.
[German] |
|
| document type: |
|
| institution: |
| Faculty of Mathematics and Natural Sciences |
|
| language: |
|
| subject class (DDC): |
| 590 Zoological sciences |
| 570 Life science |
|
| |
publication /
production: |
Rostock
|
Rostock: Universität Rostock
|
|
2009
|
|
| |
| identifiers: |
|
| |
| access condition: |
|
| license/rights statement: |
all rights reserved
This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz). |
|
|
| RosDok id: |
rosdok_disshab_0000000298 |
| created / modified: |
21.04.2010 / 08.08.2023
|
| metadata license: |
The metadata of this document was dedicated to the public domain
(CC0 1.0 Universal Public Domain Dedication). |
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