goto contents

Christian Klopsch

Die intrakardiale Wirkung von Erythropoietin nach künstlicher Induktion eines Myokardinfarkts im Rattenmodell

Universität Rostock, 2008

Abstract: Studies underline positive effects of Erythropoietin in myocardial ischemia. Herein, an intracardiac Erythropoietin therapy (MI-EPO) following myocardial infarction in rats was examined versus an infarction control group (MIC) and healthy animals. Physiological and biochemical testing throughout 6 weeks revealed enhancements in global cardiac function, physics, infarction size, cytoprotection and myocardial remodeling in MI-EPO compared to MIC. For the first time, an induction of SDF-1 and stem cell chemoattraction were documented and could be responsible in part.

doctoral thesis   free access    


OPACGVKDataCite Commons


all rights reserved

This work may only be used under the terms of the German Copyright Law (Urheberrechtsgesetz).