| title: |
| Positive stranded RNA viruses: Dissecting the capsid of Hepatitis E and Chikungunya
viruses |
|
| contributing persons: |
| Saijo Thomas[VerfasserIn] |
 |
143547151 |
| Stephan Schaefer
, Prof. Dr. med.[AkademischeR BetreuerIn] |
| Hubert Bahl
, Prof. Dr. rer. nat.[AkademischeR BetreuerIn] |
|
| contributing corporate bodies: |
| Universität Rostock, Mathematisch-Naturwissenschaftliche Fakultät[Grad-verleihende Institution] |
|
2147083-2 |
|
| |
| abstract: |
|
Capsid protein of two positive stranded RNA viruses, Hepatitis E virus (HEV) and Chikungunya
virus (ChikV), were investigated. HEV was detected in swine serum collected in Germany.
An infectious system for HEV was established and was used to check its egress. The
requirement of various amino acid sequences for the autoproteolytic cleavage of ChikV
capsid protease was investigated. I was also able to show that ChikV capsid is recognized
by karyopherins and its export is mediated by CRM1 dependent nuclear export signal.
[Englisch] |
|
| document type: |
|
| institution: |
| Mathematisch-Naturwissenschaftliche Fakultät |
|
| language: |
|
| subject class (DDC): |
| 610 Medizin, Gesundheit |
| 570 Biowissenschaften, Biologie |
|
| |
publication /
production: |
|
Rostock: Universität Rostock
|
|
2010
|
|
| |
| identifiers: |
|
| |
| access condition: |
|
frei zugänglich (Open Access)
|
|
| license/rights statement: |
alle Rechte vorbehalten
Das Werk darf ausschließlich nach den vom deutschen Urheberrechtsgesetz festgelegten Bedingungen genutzt werden. |
|
|
| RosDok-ID: |
rosdok_disshab_0000000597 |
| created / modified: |
13.03.2012 / 08.08.2023
|
| metadata license: |
Die Metadaten zu diesem Dokument sind gemeinfrei
(CC0 1.0 Universal Public Domain Dedication). |
Zugang
viewer
fulltext